PDB entry 2psq

View 2psq on RCSB PDB site
Description: Crystal Structure of Unphosphorylated Unactivated Wild Type FGF Receptor 2 (FGFR2) Kinase Domain
Class: transferase
Keywords: Kinase Domain Fold Consisting of N- and C-lobes, TRANSFERASE
Deposited on 2007-05-07, released 2007-09-25
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.211
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fibroblast growth factor receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: FGFR2, BEK, KSAM
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2psqa1
  • Chain 'B':
    Compound: Fibroblast growth factor receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: FGFR2, BEK, KSAM
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2psqb1
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2psqA (A:)
mgsshhhhhhsqdppavhkltkriplrrqvtvsaessssmnsntplvrittrlsstadtp
mlagvseyelpedpkwefprdkltlgkplgegcfgqvvmaeavgidkdkpkeavtvavkm
lkddatekdlsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylra
rrppgmeysydinrvpeeqmtfkdlvsctyqlargmeylasqkcihrdlaarnvlvtenn
vmkiadfglardinnidyykkttngrlpvkwmapealfdrvythqsdvwsfgvlmweift
lggspypgipveelfkllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedld
riltlttnee

    Sequence, based on observed residues (ATOM records): (download) 
    >2psqA (A:)
lpedpkwefprdkltlgkplgegcfgqvvmaeavgidkdkpkeavtvavkmlkddatekd
lsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarrpppeeqm
tfkdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfglardinnidyyk
kttngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypgipveelfkllke
ghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltltt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2psqB (B:)
mgsshhhhhhsqdppavhkltkriplrrqvtvsaessssmnsntplvrittrlsstadtp
mlagvseyelpedpkwefprdkltlgkplgegcfgqvvmaeavgidkdkpkeavtvavkm
lkddatekdlsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylra
rrppgmeysydinrvpeeqmtfkdlvsctyqlargmeylasqkcihrdlaarnvlvtenn
vmkiadfglardinnidyykkttngrlpvkwmapealfdrvythqsdvwsfgvlmweift
lggspypgipveelfkllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedld
riltlttnee

    Sequence, based on observed residues (ATOM records): (download) 
    >2psqB (B:)
elpedpkwefprdkltlgkplgegcfgqvvmaeavgidpkeavtvavkmlkddatekdls
dlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarrppgeeqmtf
kdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfglardinnidyykkt
tngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypgipveelfkllkegh
rmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlttn