PDB entry 2orv

View 2orv on RCSB PDB site
Description: human Thymidine Kinase 1 in complex with TP4A
Class: transferase
Keywords: tk-1 (thymidine kinase 1), tp4a (p1-(5'-adenosyl)p4-(5'-(2'deoxythymidil))tetraphosphate, transferase
Deposited on 2007-02-04, released 2007-03-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.202
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidine kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: TK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2orva1, d2orva2
  • Chain 'B':
    Compound: Thymidine kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: TK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2orvb1, d2orvb2
  • Heterogens: ZN, 4TA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2orvA (A:)
mscinlptvlpgspsktrgqiqvilgpmfsgkstelmrrvrrfqiaqykclvikyakdtr
ysssfcthdrntmealpacllrdvaqealgvavigidegqffpdivefceamanagktvi
vaaldgtfqrkpfgailnlvplaesvvkltavcmecfreaaytkrlgtekeveviggadk
yhsvcrlcyfkkasgqpagpdnaancpvpgkpgeavaarklfapqqilqcspan

    Sequence, based on observed residues (ATOM records): (download) 
    >2orvA (A:)
rgqiqvilgpmfsgkstelmrrvrrfqiaqykclvikyakdtrymealpacllrdvaqea
lgvavigidegqffpdivefceamanagktvivaaldgtfqrkpfgailnlvplaesvvk
ltavcmecfreaaytkrlgtekeveviggadkyhsvcrlcyfk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2orvB (B:)
mscinlptvlpgspsktrgqiqvilgpmfsgkstelmrrvrrfqiaqykclvikyakdtr
ysssfcthdrntmealpacllrdvaqealgvavigidegqffpdivefceamanagktvi
vaaldgtfqrkpfgailnlvplaesvvkltavcmecfreaaytkrlgtekeveviggadk
yhsvcrlcyfkkasgqpagpdnaancpvpgkpgeavaarklfapqqilqcspan

    Sequence, based on observed residues (ATOM records): (download) 
    >2orvB (B:)
rgqiqvilgpmfsgkstelmrrvrrfqiaqykclvikyakdmealpacllrdvaqealgv
avigidegqffpdivefceamanagktvivaaldgtfqrkpfgailnlvplaesvvklta
vcmecfreaaytkrlgtekeveviggadkyhsvcrlcyfk