PDB entry 2kbw

View 2kbw on RCSB PDB site
Description: Solution Structure of human Mcl-1 complexed with human Bid_BH3 peptide
Class: apoptosis
Keywords: Mcl-1, Bid_BH3, complex, Apoptosis, Developmental protein, Differentiation, Membrane, Mitochondrion, Nucleus, Phosphoprotein, Transmembrane
Deposited on 2008-12-09, released 2009-12-15
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-06-30, with a file datestamp of 2010-06-25.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.02 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, Myeloid Cell Leukemia 1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2kbwa_
  • Chain 'B':
    Compound: BH3-interacting domain death agonist
    Species: Homo sapiens [TaxId:9606]
    Gene: BID
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2kbwA (A:)
    tpppaeeeedelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqr
    nhetafqgmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktin
    qescieplaesitdvlvrtkrdwlvkqrgwdgfveffhvedleg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2kbwA (A:)
    aeeeedelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhet
    afqgmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesc
    ieplaesitdvlvrtkrdwlvkqrgwdgfveffhvedleg
    

  • Chain 'B':
    No sequence available.