PDB entry 2ixg

View 2ixg on RCSB PDB site
Description: crystal structure of the ATPase domain of tap1 with ATP (s621a, g622v, d645n mutant)
Class: hydrolase
Keywords: hydrolase, endoplasmic reticulum, membrane, transport, abc ATPase, ATP- binding, protein transport, nucleotide-binding, transmembrane, immune response, peptide transport
Deposited on 2006-07-08, released 2006-10-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.217
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: antigen peptide transporter 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IXG
      • engineered mutation (157-158)
      • engineered mutation (181)
    • Uniprot P36370
    Domains in SCOPe 2.07: d2ixga_
  • Heterogens: ATP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ixgA (A:)
msplsgslaplnmkglvkfqdvsfaypnhpnvqvlqgltftlypgkvtalvgpngsgkst
vaallqnlyqptggkvlldgeplvqydhhylhtqvaavgqepllfgrsfreniaygltrt
ptmeeitavamesgahdfisgfpqgydtevgetgnqlavgqrqavalaralirkprllil
dnatsaldagnqlrvqrllyespewasrtvllitqqlslaerahhilflkegsvceqgth
lqlmerggcyrsmvealaapsdaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2ixgA (A:)
lsgslaplnmkglvkfqdvsfaypnhpnvqvlqgltftlypgkvtalvgpngsgkstvaa
llqnlyqptggkvlldgeplvqydhhylhtqvaavgqepllfgrsfreniaygltrtptm
eeitavamesgahdfisgfpqgydtevgetgnqlavgqrqavalaralirkprllildna
tsaldagnqlrvqrllyespewasrtvllitqqlslaerahhilflkegsvceqgthlql
merggcyrsmveal