PDB entry 2hkj

View 2hkj on RCSB PDB site
Description: Topoisomerase VI-B bound to radicicol
Class: isomerase
Keywords: topoisomerase, ghkl, drug complex, radicicol, ISOMERASE
Deposited on 2006-07-04, released 2006-08-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.17
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Type II DNA topoisomerase VI subunit B
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6B
    Database cross-references and differences (RAF-indexed):
    • Uniprot O05207 (Start-468)
      • see remark 999 (301)
      • see remark 999 (433)
    Domains in SCOPe 2.07: d2hkja1, d2hkja2, d2hkja3
  • Heterogens: MG, DMS, RDC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2hkjA (A:)
sakekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikitid
liddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqm
hqdkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipgdwp
kaksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdreei
kilinnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfk
kyedfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggs
ipvgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstkip
yksagkesiaevediekeiknalmevarklkqylsekrkeqeakkklla

    Sequence, based on observed residues (ATOM records): (download) 
    >2hkjA (A:)
lspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikitidliddarqi
ykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqmhqdkpiei
etspvnskriytfklkidinknepiivergsventrgfhgtsvaisipgdwpkaksriye
yikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdreeikilinnlk
rdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfkkyedfrsp
sadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggsipvgeepi
vlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstkipyksagkes
iaevediekeiknalmevarklkqylsekrkeqeakkklla