PDB entry 2fxs

View 2fxs on RCSB PDB site
Description: Yeast HSP82 in complex with the novel HSP90 Inhibitor Radamide
Class: chaperone
Keywords: HSP82, HSP90, GRP94, HTPG, chaperone, ligand, radicicol, geldanamycin, radester
Deposited on 2006-02-06, released 2007-02-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.196
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent molecular chaperone hsp82
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: HSP82, HSP90
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2fxsa2, d2fxsa3
  • Heterogens: RDA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2fxsA (A:)
mgsshhhhhhssglvprgshmasetfefqaeitqlmsliintvysnkeiflrelisnasd
aldkirykslsdpkqletepdlfiritpkpeqkvleirdsgigmtkaelinnlgtiaksg
tkafmealsagadvsmigqfgvgfyslflvadrvqvisksnddeqyiwesnaggsftvtl
devnerigrgtilrlflkddqleyleekrikevikrhsefvaypiqlvvtkevekevpip

    Sequence, based on observed residues (ATOM records): (download) 
    >2fxsA (A:)
asetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletepd
lfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqfg
vgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddq
leyleekrikevikrhsefvaypiqlvvtkeve