PDB entry 2bcd

View 2bcd on RCSB PDB site
Description: X-ray crystal structure of Protein Phosphatase-1 with the marine toxin motuporin bound
Class: hydrolase/hydrolase inhibitor
Keywords: Protein phosphtase, natural product inhibitors, motuporin, nodularin, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on 2005-10-19, released 2006-01-17
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-27, with a file datestamp of 2011-07-22.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.223
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine protein phosphatase pp1-gamma catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: Ppp1cc
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2bcda_
  • Chain 'B':
    Compound: motuporin
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00825 (0-4)
  • Heterogens: BME, MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bcdA (A:)
madldklnidsiiqrllevrgskpgknvqlqeneirglclksreiflsqpilleleaplk
icgdihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffl
lrgnhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdl
qsmeqirrimrptdvpdqgllcdllwsdpdkdvlgwgendrgvsftfgaevvakflhkhd
ldlicrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpae
kkkpnatrpvtpprgmitkqakk

    Sequence, based on observed residues (ATOM records): (download) 
    >2bcdA (A:)
klnidsiiqrllevrgskpgknvqlqeneirglclksreiflsqpilleleaplkicgdi
hgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnh
ecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeq
irrimrptdvpdqgllcdllwsdpdkdvlgwgendrgvsftfgaevvakflhkhdldlic
rahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkp

  • Chain 'B':
    No sequence available.