PDB entry 2axf

View 2axf on RCSB PDB site
Description: The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation
Class: immune system/gene regulation
Keywords: immune response, pMHC, IMMUNE SYSTEM/GENE REGULATION COMPLEX
Deposited on 2005-09-05, released 2005-11-29
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.208
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: HLA class I histocompatibility antigen, B*3508 heavy chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P30685 (0-275)
    • see remark 999 (155)
  Domains in SCOPe 2.04: d2axfa1, d2axfa2
• Chain 'B':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (0-98)
  Domains in SCOPe 2.04: d2axfb_
• Chain 'C':
  Compound: 10-mer peptide from BZLF1 trans-activator protein
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03206 (0-9)
• Heterogens: ACY, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2axfA (A:)
  gshsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeyw
  drntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydg
  kdyialnedlsswtaadtaaqitqrkweaarvaeqrrayleglcvewlrrylengketlq
  radppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
  fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2axfB (B:)
  iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
  sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'C':
  No sequence available.