PDB entry 2ao4

View 2ao4 on RCSB PDB site
Description: Structure of 2C-Methyl-D-Erythritol 2,4-Clycodiphosphate Synthase complexed with a CDP derived fluorescent inhibitor
Class: Lyase
Keywords: isoprenoid, lyase, isoprene biosynthesis
Deposited on 2005-08-12, released 2006-02-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2006-11-14, with a file datestamp of 2007-04-25.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.223
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Escherichia coli
    Gene: ispF, mecS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62617 (2-End)
      • cloning artifact (0-1)
    Domains in SCOPe 2.07: d2ao4a1, d2ao4a2
  • Heterogens: ZN, 2AA, GPP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ao4A (A:)
lemrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdig
klfpdtdpafkgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfiae
dlgchmddvnvkattteklgftgrgegiaceavallikatk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ao4A (A:)
lemrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdig
klfpdtdpafkgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfiae
dlgchmddvnvkattteklgftgrgegiaceavallika