PDB entry 2aik

View 2aik on RCSB PDB site
Description: Formylglycine generating enzyme C336S mutant covalently bound to substrate peptide LCTPSRA
Class: hydrolase activator,protein binding
Keywords: formylglycine, post-translational modification, endoplasmic reticulum, sulfatase, HYDROLASE ACTIVATOR,PROTEIN BINDING
Deposited on 2005-07-29, released 2005-12-13
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.73 Å
R-factor: 0.142
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'P':
    Compound: LCTPSRA peptide from Arylsulfatase A
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'X':
    Compound: Sulfatase modifying factor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NBK3 (0-285)
      • engineered (250)
    Domains in SCOPe 2.04: d2aikx_
  • Heterogens: CA, CL, HOH

PDB Chain Sequences:

  • Chain 'P':
    No sequence available.

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >2aikX (X:)
lahskmvpipagvftmgtddpqikqdgeaparrvtidafymdayevsntefekfvnstgy
lteaekfgdsfvfegmlseqvktniqqavaaapwwlpvkganwrhpegpdstilhrpdhp
vlhvswndavayctwagkrlpteaeweyscrgglhnrlfpwgnklqpkgqhyaniwqgef
pvtntgedgfqgtapvdafppngyglynivgnawewtsdwwtvhhsveetlnpkgppsgk
drvkkggsymshrsycyryrcaarsqntpdssasnlgfrcaadrlp

    Sequence, based on observed residues (ATOM records): (download) 
    >2aikX (X:)
lahskmvpipagvftmgtddpqikqdgeaparrvtidafymdayevsntefekfvnstgy
lteaekfgdsfvfegmlaaapwwlpvkganwrhpegpdstilhrpdhpvlhvswndavay
ctwagkrlpteaeweyscrgglhnrlfpwgnklqpkgqhyaniwqgefpvtntgedgfqg
tapvdafppngyglynivgnawewtsdwwtvhhsveetlnpkgppsgkdrvkkggsymsh
rsycyryrcaarsqntpdssasnlgfrcaadrlp