PDB entry 1t9d

View 1t9d on RCSB PDB site
Description: Crystal Structure Of Yeast Acetohydroxyacid Synthase In Complex With A Sulfonylurea Herbicide, Metsulfuron methyl
Class: transferase
Keywords: acetohydroxyacid synthase, acetolactate synthase, herbicide, sulfonylurea, thiamin diphosphate, FAD, inhibitor, metsulfuron methyl, transferase
Deposited on 2004-05-16, released 2004-12-21
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-09-01, with a file datestamp of 2009-08-28.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.164
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetolactate synthase, mitochondrial
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: ILV2, SMR1, YMR108W, YM9718.07
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1t9da1, d1t9da2, d1t9da3
  • Chain 'B':
    Compound: Acetolactate synthase, mitochondrial
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: ILV2, SMR1, YMR108W, YM9718.07
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1t9db1, d1t9db2, d1t9db3
  • Chain 'C':
    Compound: Acetolactate synthase, mitochondrial
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: ILV2, SMR1, YMR108W, YM9718.07
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1t9dc1, d1t9dc2, d1t9dc3
  • Chain 'D':
    Compound: Acetolactate synthase, mitochondrial
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: ILV2, SMR1, YMR108W, YM9718.07
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1t9dd1, d1t9dd2, d1t9dd3
  • Heterogens: K, MG, 1MM, P25, FAD, PYD, P22, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1t9dA (A:)
mhhhhhhssglvprgsgmketaaakferqhmdspdlgtddddkamgsapsfnvdpleqpa
epsklakklraepdmdtsfvgltggqifnemmsrqnvdtvfgypggailpvydaihnsdk
fnfvlpkheqgaghmaegyarasgkpgvvlvtsgpgatnvvtpmadafadgipmvvftgq
vptsaigtdafqeadvvgisrsctkwnvmvksveelplrineafeiatsgrpgpvlvdlp
kdvtaailrnpiptkttlpsnalnqltsraqdefvmqsinkaadlinlakkpvlyvgagi
lnhadgprllkelsdraqipvtttlqglgsfdqedpksldmlgmhgcatanlavqnadli
iavgarfddrvtgniskfapearraaaegrggiihfevspkninkvvqtqiavegdattn
lgkmmskifpvkersewfaqinkwkkeypyaymeetpgskikpqtvikklskvandtgrh
vivttgvgqhqmwaaqhwtwrnphtfitsgglgtmgyglpaaigaqvakpeslvididgd
asfnmtltelssavqagtpvkililnneeqgmvtqwqslfyehryshthqlnpdfiklae
amglkglrvkkqeeldaklkefvstkgpvllevevdkkvpvlpmvaggsgldefinfdpe
verqqtelrhkrtggkh

    Sequence, based on observed residues (ATOM records): (download) 
    >1t9dA (A:)
mdtsfvgltggqifnemmsrqnvdtvfgypggailpvydaihnsdkfnfvlpkheqgagh
maegyarasgkpgvvlvtsgpgatnvvtpmadafadgipmvvftgqvptsaigtdafqea
dvvgisrsctkwnvmvksveelplrineafeiatsgrpgpvlvdlpkdvtaailrnpipt
kttlptsraqdefvmqsinkaadlinlakkpvlyvgagilnhadgprllkelsdraqipv
tttlqglgsfdqedpksldmlgmhgcatanlavqnadliiavgarfddrvtgniskfape
arraaaegrggiihfevspkninkvvqtqiavegdattnlgkmmskifpvkersewfaqi
nkwkkeypyaymeetpgskikpqtvikklskvandtgrhvivttgvgqhqmwaaqhwtwr
nphtfitsgglgtmgyglpaaigaqvakpeslvididgdasfnmtltelssavqagtpvk
ililnneeqgmvtqwqslfyehryshthqlnpdfiklaeamglkglrvkkqeeldaklke
fvstkgpvllevevdkkvpvlpmvaggsgldefinfdpeverqqtelrhkrtggkh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1t9dB (B:)
mhhhhhhssglvprgsgmketaaakferqhmdspdlgtddddkamgsapsfnvdpleqpa
epsklakklraepdmdtsfvgltggqifnemmsrqnvdtvfgypggailpvydaihnsdk
fnfvlpkheqgaghmaegyarasgkpgvvlvtsgpgatnvvtpmadafadgipmvvftgq
vptsaigtdafqeadvvgisrsctkwnvmvksveelplrineafeiatsgrpgpvlvdlp
kdvtaailrnpiptkttlpsnalnqltsraqdefvmqsinkaadlinlakkpvlyvgagi
lnhadgprllkelsdraqipvtttlqglgsfdqedpksldmlgmhgcatanlavqnadli
iavgarfddrvtgniskfapearraaaegrggiihfevspkninkvvqtqiavegdattn
lgkmmskifpvkersewfaqinkwkkeypyaymeetpgskikpqtvikklskvandtgrh
vivttgvgqhqmwaaqhwtwrnphtfitsgglgtmgyglpaaigaqvakpeslvididgd
asfnmtltelssavqagtpvkililnneeqgmvtqwqslfyehryshthqlnpdfiklae
amglkglrvkkqeeldaklkefvstkgpvllevevdkkvpvlpmvaggsgldefinfdpe
verqqtelrhkrtggkh

    Sequence, based on observed residues (ATOM records): (download) 
    >1t9dB (B:)
dtsfvgltggqifnemmsrqnvdtvfgypggailpvydaihnsdkfnfvlpkheqgaghm
aegyarasgkpgvvlvtsgpgatnvvtpmadafadgipmvvftgqvptsaigtdafqead
vvgisrsctkwnvmvksveelplrineafeiatsgrpgpvlvdlpkdvtaailrnpipfv
mqsinkaadlinlakkpvlyvgagilnhadgprllkelsdraqipvtttlqglgsfdqed
pksldmlgmhgcatanlavqnadliiavgarfddrvtgniskfapearraaaegrggiih
fevspkninkvvqtqiavegdattnlgkmmskifpvkersewfaqinkwkkeypyaymee
tpgskikpqtvikklskvandtgrhvivttgvgqhqmwaaqhwtwrnphtfitsgglgtm
gyglpaaigaqvakpeslvididgdasfnmtltelssavqagtpvkililnneeqgmvtq
wqslfyehryshthqlnpdfiklaeamglkglrvkkqeeldaklkefvstkgpvllevev
dkkvpvlpmvaggsgldefinfdpeverqqtelrhkrtggkh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1t9dC (C:)
mhhhhhhssglvprgsgmketaaakferqhmdspdlgtddddkamgsapsfnvdpleqpa
epsklakklraepdmdtsfvgltggqifnemmsrqnvdtvfgypggailpvydaihnsdk
fnfvlpkheqgaghmaegyarasgkpgvvlvtsgpgatnvvtpmadafadgipmvvftgq
vptsaigtdafqeadvvgisrsctkwnvmvksveelplrineafeiatsgrpgpvlvdlp
kdvtaailrnpiptkttlpsnalnqltsraqdefvmqsinkaadlinlakkpvlyvgagi
lnhadgprllkelsdraqipvtttlqglgsfdqedpksldmlgmhgcatanlavqnadli
iavgarfddrvtgniskfapearraaaegrggiihfevspkninkvvqtqiavegdattn
lgkmmskifpvkersewfaqinkwkkeypyaymeetpgskikpqtvikklskvandtgrh
vivttgvgqhqmwaaqhwtwrnphtfitsgglgtmgyglpaaigaqvakpeslvididgd
asfnmtltelssavqagtpvkililnneeqgmvtqwqslfyehryshthqlnpdfiklae
amglkglrvkkqeeldaklkefvstkgpvllevevdkkvpvlpmvaggsgldefinfdpe
verqqtelrhkrtggkh

    Sequence, based on observed residues (ATOM records): (download) 
    >1t9dC (C:)
fvgltggqifnemmsrqnvdtvfgypggailpvydaihnsdkfnfvlpkheqgaghmaeg
yarasgkpgvvlvtsgpgatnvvtpmadafadgipmvvftgqvptsaigtdafqeadvvg
isrsctkwnvmvksveelplrineafeiatsgrpgpvlvdlpkdvtaailrnpiptknka
adlinlakkpvlyvgagilnhadgprllkelsdraqipvtttlqglgsfdqedpksldml
gmhgcatanlavqnadliiavgarfddrvtgniskfapearraaaegrggiihfevspkn
inkvvqtqiavegdattnlgkmmskifpvkersewfaqinkwkkeypyaymeetpgskik
pqtvikklskvandtgrhvivttgvgqhqmwaaqhwtwrnphtfitsgglgtmgyglpaa
igaqvakpeslvididgdasfnmtltelssavqagtpvkililnneeqgmvtqwqslfye
hryshthqlnpdfiklaeamglkglrvkkqeeldaklkefvstkgpvllevevdkkvpvl
pmvaggsgldefinfdpeverqqtelrhkrtggkh

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1t9dD (D:)
mhhhhhhssglvprgsgmketaaakferqhmdspdlgtddddkamgsapsfnvdpleqpa
epsklakklraepdmdtsfvgltggqifnemmsrqnvdtvfgypggailpvydaihnsdk
fnfvlpkheqgaghmaegyarasgkpgvvlvtsgpgatnvvtpmadafadgipmvvftgq
vptsaigtdafqeadvvgisrsctkwnvmvksveelplrineafeiatsgrpgpvlvdlp
kdvtaailrnpiptkttlpsnalnqltsraqdefvmqsinkaadlinlakkpvlyvgagi
lnhadgprllkelsdraqipvtttlqglgsfdqedpksldmlgmhgcatanlavqnadli
iavgarfddrvtgniskfapearraaaegrggiihfevspkninkvvqtqiavegdattn
lgkmmskifpvkersewfaqinkwkkeypyaymeetpgskikpqtvikklskvandtgrh
vivttgvgqhqmwaaqhwtwrnphtfitsgglgtmgyglpaaigaqvakpeslvididgd
asfnmtltelssavqagtpvkililnneeqgmvtqwqslfyehryshthqlnpdfiklae
amglkglrvkkqeeldaklkefvstkgpvllevevdkkvpvlpmvaggsgldefinfdpe
verqqtelrhkrtggkh

    Sequence, based on observed residues (ATOM records): (download) 
    >1t9dD (D:)
mdtsfvgltggqifnemmsrqnvdtvfgypggailpvydaihnsdkfnfvlpkheqgagh
maegyarasgkpgvvlvtsgpgatnvvtpmadafadgipmvvftgqvptsaigtdafqea
dvvgisrsctkwnvmvksveelplrineafeiatsgrpgpvlvdlpkdvtaailrnpipt
kttlpssraqdefvmqsinkaadlinlakkpvlyvgagilnhadgprllkelsdraqipv
tttlqglgsfdqedpksldmlgmhgcatanlavqnadliiavgarfddrvtgniskfape
arraaaegrggiihfevspkninkvvqtqiavegdattnlgkmmskifpvkersewfaqi
nkwkkeypyaymeetpgskikpqtvikklskvandtgrhvivttgvgqhqmwaaqhwtwr
nphtfitsgglgtmgyglpaaigaqvakpeslvididgdasfnmtltelssavqagtpvk
ililnneeqgmvtqwqslfyehryshthqlnpdfiklaeamglkglrvkkqeeldaklke
fvstkgpvllevevdkkvpvlpmvaggsgldefinfdpeverqqtelrhkrtggkh