PDB entry 1rzk

View 1rzk on RCSB PDB site
Description: hiv-1 yu2 gp120 envelope glycoprotein complexed with cd4 and induced neutralizing antibody 17b
Class: Viral protein/Immune system
Keywords: complex (hiv envelope protein/cd4/fab); hiv-1 exterior envelope gp120 from laboratory-adapted isolate; hxbc2; surface T-cell glycoprotein cd4; antigen-binding fragment of human immunoglobulin 17b
Deposited on 2003-12-24, released 2004-02-03
The last revision prior to the SCOP 1.73 freeze date was dated 2005-02-01, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.205
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: T-cell surface glycoprotein cd4
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1rzkc1, d1rzkc2
  • Chain 'G':
    Compound: envelope glycoprotein gp120
    Species: Human immunodeficiency virus 1
    Domains in SCOP 1.73: d1rzkg_
  • Chain 'H':
    Compound: antibody 17b, heavy chain
    Species: HOMO SAPIENS
    Domains in SCOP 1.73: d1rzkh1, d1rzkh2
  • Chain 'L':
    Compound: antibody 17b, light chain
    Species: HOMO SAPIENS
    Domains in SCOP 1.73: d1rzkl1, d1rzkl2
  • Heterogens: NDG, NAG, HOH

PDB Chain Sequences:

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1rzkC (C:)
kkvvlgkkgdtveltctasqkksiqfhwknsnqikilgnqgsfltkgpsklndradsrrs
lwdqgnfpliiknlkiedsdtyicevedqkeevqllvfgltansdthllqgqsltltles
ppgsspsvqcrsprgkniqggktlsvsqlelqdsgtwtctvlqnqkkvefkidivvlafq
kasnt

    Sequence, based on observed residues (ATOM records): (download) 
    >1rzkC (C:)
kkvvlgkkgdtveltctasqkksiqfhwknsnqikilgnqgsfltkgpsklndradsrrs
lwdqgnfpliiknlkiedsdtyicevedqkeevqllvfgltansdthllqgqsltltles
ppgsspsvqcrsprgkniqggktlsvsqlelqdsgtwtctvlqnqkkvefkidivvlafq
k

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1rzkG (G:)
garsevklenvtenfnmwknnmveqmhediislwdqslkpcvkltplcvgagscntsvit
qacpkvsfepipihycapagfailkcndkkfngtgpctnvstvqcthgirpvvstqllln
gslaeeeivirsenftnnaktiivqlnesvvinctgaghcnlsktqwentleqiaiklke
qfgnnktiifnpssggdpeivthsfncggeffycnstqlftwndtrklnntgrnitlpcr
ikqiinmwqevgkamyappirgqircssnitgllltrdggkdtngteifrpgggdmrdnw
rselykykvvkie

    Sequence, based on observed residues (ATOM records): (download) 
    >1rzkG (G:)
lenvtenfnmwknnmveqmhediislwdqslkpcvkltplcvgagscntsvitqacpkvs
fepipihycapagfailkcndkkfngtgpctnvstvqcthgirpvvstqlllngslaeee
ivirsenftnnaktiivqlnesvvinctgaghcnlsktqwentleqiaiklkeqfgnnkt
iifnpssggdpeivthsfncggeffycnstqlftwndtrklnntgrnitlpcrikqiinm
wqevgkamyappirgqircssnitgllltrdggkdtngteifrpgggdmrdnwrselyky
kvvkie

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rzkH (H:)
evqlvesgaevkkpgssvkvsckasgdtfirysftwvrqapgqglewmgriitildvahy
aphlqgrvtitadkststvylelrnlrsddtavyfcagvyegeadegeydnngflkhwgq
gtlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvht
fpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rzkL (L:)
divmtqspatlsvspgeratlscrasesvssdlawyqqkpgqaprlliygastratgvpa
rfsgsgsgaeftltisslqsedfavyycqqynnwpprytfgqgtrleikrtvaapsvfif
ppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsst
ltlskadyekhkvyacevthqglsspvtksfnrg