PDB entry 1pwv

View 1pwv on RCSB PDB site
Description: Crystal structure of Anthrax Lethal Factor wild-type protein complexed with an optimised peptide substrate.
Class: hydrolase
Keywords: Anthrax Toxin, Lethal Factor, optimised peptide substrate, hydrolase
Deposited on 2003-07-02, released 2004-02-03
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: 0.231
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lethal Factor
    Species: Bacillus anthracis [TaxId:1392]
    Gene: LEF OR PXO1-107
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1pwva1, d1pwva2, d1pwva3
  • Chain 'B':
    Compound: Lethal Factor
    Species: Bacillus anthracis [TaxId:1392]
    Gene: LEF OR PXO1-107
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1pwvb1, d1pwvb2, d1pwvb3
  • Chain 'C':
    Compound: lf20
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1PWV
  • Chain 'D':
    Compound: lf20
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1PWV

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pwvA (A:)
agghgdvgmhvkekeknkdenkrkdeernktqeehlkeimkhivkievkgeeavkkeaae
kllekvpsdvlemykaiggkiyivdgditkhislealsedkkkikdiygkdallhehyvy
akegyepvlviqssedyventekalnvyyeigkilsrdilskinqpyqkfldvlntikna
sdsdgqdllftnqlkehptdfsvefleqnsnevqevfakafayyiepqhrdvlqlyapea
fnymdkfneqeinlsleelkdqrmlsryekwekikqhyqhwsdslseegrgllkklqipi
epkkddiihslsqeekellkriqidssdflsteekeflkklqidirdslseeekellnri
qvdssnplsekekeflkklkldiqpydinqrlqdtgglidspsinldvrkqykrdiqnid
allhqsigstlynkiylyenmninnltatlgadlvdstdntkinrgifnefkknfkysis
snymivdinerpaldnerlkwriqlspdtragylengklilqrnigleikdvqiikqsek
eyiridakvvpkskidtkiqeaqlninqewnkalglpkytklitfnvhnryasnivesay
lilnewknniqsdlikkvtnylvdgngrfvftditlpniaeqythqdeiyeqvhskglyv
pesrsillhgpskgvelrndsegfihefghavddyagylldknqsdlvtnskkfidifke
egsnltsygrtneaeffaeafrlmhstdhaerlkvqknapktfqfindqikfiins

    Sequence, based on observed residues (ATOM records): (download) 
    >1pwvA (A:)
ernktqeehlkeimkhivkievkgeeavkkeaaekllekvpsdvlemykaiggkiyivdg
ditkhislealsedkkkikdiygkdallhehyvyakegyepvlviqssedyventekaln
vyyeigkilsrdilskinqpyqkfldvlntiknasdsdgqdllftnqlkehptdfsvefl
eqnsnevqevfakafayyiepqhrdvlqlyapeafnymdkfneqeinlsleelkdqrmls
ryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriqids
sdflsteekeflkklqidirdslplsekekeflkklkldiqpydinqrlqdtgglidsps
inldvrkqykrdiqnidallhqsigstlynkiylyenmninnltatlgadlvdstdntki
nrgifnefkknfkysissnymivdinerpaldnerlkwriqlspdtragylengklilqr
nigleikdvqiikqsekeyiridakvvpkskidtkiqeaqlninqewnkalglpkytkli
tfnvhnryasnivesaylilnewknniqsdlikkvtnylvdgngrfvftditlpniaeqy
thqdeiyeqvhskglyvpesrsillhgpskgvelrndsegfihefghavddyagylldkn
qsdlvtnskkfidifkeegsnltsygrtneaeffaeafrlmhstdhaerlkvqknapktf
qfindqikfiins

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1pwvB (B:)
agghgdvgmhvkekeknkdenkrkdeernktqeehlkeimkhivkievkgeeavkkeaae
kllekvpsdvlemykaiggkiyivdgditkhislealsedkkkikdiygkdallhehyvy
akegyepvlviqssedyventekalnvyyeigkilsrdilskinqpyqkfldvlntikna
sdsdgqdllftnqlkehptdfsvefleqnsnevqevfakafayyiepqhrdvlqlyapea
fnymdkfneqeinlsleelkdqrmlsryekwekikqhyqhwsdslseegrgllkklqipi
epkkddiihslsqeekellkriqidssdflsteekeflkklqidirdslseeekellnri
qvdssnplsekekeflkklkldiqpydinqrlqdtgglidspsinldvrkqykrdiqnid
allhqsigstlynkiylyenmninnltatlgadlvdstdntkinrgifnefkknfkysis
snymivdinerpaldnerlkwriqlspdtragylengklilqrnigleikdvqiikqsek
eyiridakvvpkskidtkiqeaqlninqewnkalglpkytklitfnvhnryasnivesay
lilnewknniqsdlikkvtnylvdgngrfvftditlpniaeqythqdeiyeqvhskglyv
pesrsillhgpskgvelrndsegfihefghavddyagylldknqsdlvtnskkfidifke
egsnltsygrtneaeffaeafrlmhstdhaerlkvqknapktfqfindqikfiins

    Sequence, based on observed residues (ATOM records): (download) 
    >1pwvB (B:)
eehlkeimkhivkievkgeeavkkeaaekllekvpsdvlemykaiggkiyivdgditkhi
slealsedkkkikdiygkdallhehyvyakegyepvlviqssedyventekalnvyyeig
kilsrdilskinqpyqkfldvlntiknasdsdgqdllftnqlkehptdfsvefleqnsne
vqevfakafayyiepqhrdvlqlyapeafnymdkfneqeinlsleelkdqrmlsryekwe
kikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriqidssdflst
eekeflkklqidirdslseeekellnplsekekeflkklkldiqpydinqrlqdtgglid
spsinldvrkqykrdiqnidallhqsigstlynkiylyenmninnltatlgadlvdstdn
tkinrgifnefkknfkysissnymivdinerpaldnerlkwriqlspdtragylengkli
lqrnigleikdvqiikqsekeyiridakvvpkskidtkiqeaqlninqewnkalglpkyt
klitfnvhnryasnivesaylilnewknniqsdlikkvtnylvdgngrfvftditlpnia
eqythqdeiyeqvhskglyvpesrsillhgpskgvelrndsegfihefghavddyagyll
dknqsdlvtnskkfidifkeegsnltsygrtneaeffaeafrlmhstdhaerlkvqknap
ktfqfindqikfiins

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.