PDB entry 1pg7

View 1pg7 on RCSB PDB site
Description: Murine 6A6 Fab in complex with humanized anti-Tissue Factor D3H44 Fab
Class: immune system
Keywords: immune system
Deposited on 2003-05-27, released 2003-08-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-02-05, with a file datestamp of 2014-01-31.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.217
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: humanized antibody D3H44
    Species: MUS MUSCULUS, HOMO SAPIENS [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • GB CAC51419 (0-216)
    Domains in SCOPe 2.08: d1pg7h1, d1pg7h2
  • Chain 'I':
    Compound: humanized antibody D3H44
    Species: MUS MUSCULUS, HOMO SAPIENS [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • GB CAC51419 (0-216)
    Domains in SCOPe 2.08: d1pg7i1, d1pg7i2
  • Chain 'L':
    Compound: humanized antibody D3H44
    Species: MUS MUSCULUS, HOMO SAPIENS [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • GB CAC51420 (0-212)
    Domains in SCOPe 2.08: d1pg7l1, d1pg7l2
  • Chain 'M':
    Compound: humanized antibody D3H44
    Species: MUS MUSCULUS, HOMO SAPIENS [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • GB CAC51420 (0-212)
    Domains in SCOPe 2.08: d1pg7m1, d1pg7m2
  • Chain 'W':
    Compound: murine antibody 6A6 Fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1PG7 (0-209)
    Domains in SCOPe 2.08: d1pg7w1, d1pg7w2
  • Chain 'X':
    Compound: murine antibody 6A6 Fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1PG7 (0-219)
    Domains in SCOPe 2.08: d1pg7x1, d1pg7x2
  • Chain 'Y':
    Compound: murine antibody 6A6 Fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1PG7 (0-209)
    Domains in SCOPe 2.08: d1pg7y1, d1pg7y2
  • Chain 'Z':
    Compound: murine antibody 6A6 Fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1PG7 (0-219)
    Domains in SCOPe 2.08: d1pg7z1, d1pg7z2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1pg7H (H:)
evqlvesggglvqpggslrlscaasgfnikeyymhwvrqapgkglewvglidpeqgntiy
dpkfqdratisadnskntaylqmnslraedtavyycardtaayfdywgqgtlvtvssast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

    Sequence, based on observed residues (ATOM records): (download) 
    >1pg7H (H:)
evqlvesggglvqpggslrlscaasgfnikeyymhwvrqapgkglewvglidpeqgntiy
dpkfqdratisadnskntaylqmnslraedtavyycardtaayfdywgqgtlvtvssast
kgpsvfplapssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1pg7I (I:)
evqlvesggglvqpggslrlscaasgfnikeyymhwvrqapgkglewvglidpeqgntiy
dpkfqdratisadnskntaylqmnslraedtavyycardtaayfdywgqgtlvtvssast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

    Sequence, based on observed residues (ATOM records): (download) 
    >1pg7I (I:)
evqlvesggglvqpggslrlscaasgfnikeyymhwvrqapgkglewvglidpeqgntiy
dpkfqdratisadnskntaylqmnslraedtavyycardtaayfdywgqgtlvtvssast
kgpsvfplapssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1pg7L (L:)
diqmtqspsslsasvgdrvtitcrasrdiksylnwyqqkpgkapkvliyyatslaegvps
rfsgsgsgtdytltisslqpedfatyyclqhgespwtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1pg7M (M:)
diqmtqspsslsasvgdrvtitcrasrdiksylnwyqqkpgkapkvliyyatslaegvps
rfsgsgsgtdytltisslqpedfatyyclqhgespwtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'W':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1pg7W (W:)
qavvtqesaltsspgetvtltcrsstgavttsnyanwvqekpdhlftgviggtnnrapgv
parfsgsligdkaaltitgaqtedeaiyfcalwysnhwvfgggtkltvlgqpksspsvnl
fppsseelktkkatlvctitefypgavrvdwkadgtpvtqgdettqpskqsnnkymassy
ltltaeaweshssyschvthegqsveksls

  • Chain 'X':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1pg7X (X:)
evqlqqsgpelvkpgasvkisckasgysftghllnwvkqshgknlewiglvhphngaity
nqkfkdkatltvdrssttayielvrltsndsavyycaredfryhysmdywgqgtsvtvss
akttppsvyplapvcgdttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsd
lytlsssvtvtsstwpsqsvtcnvahpasstkvdkkivpk

  • Chain 'Y':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1pg7Y (Y:)
qavvtqesaltsspgetvtltcrsstgavttsnyanwvqekpdhlftgviggtnnrapgv
parfsgsligdkaaltitgaqtedeaiyfcalwysnhwvfgggtkltvlgqpksspsvnl
fppsseelktkkatlvctitefypgavrvdwkadgtpvtqgdettqpskqsnnkymassy
ltltaeaweshssyschvthegqsveksls

  • Chain 'Z':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1pg7Z (Z:)
evqlqqsgpelvkpgasvkisckasgysftghllnwvkqshgknlewiglvhphngaity
nqkfkdkatltvdrssttayielvrltsndsavyycaredfryhysmdywgqgtsvtvss
akttppsvyplapvcgdttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsd
lytlsssvtvtsstwpsqsvtcnvahpasstkvdkkivpk