PDB entry 1p1w

View 1p1w on RCSB PDB site
Description: Crystal structure of the GluR2 ligand-binding core (S1S2J) with the L483Y and L650T mutations and in complex with AMPA
Class: membrane protein
Keywords: ionotropic glutamate receptor, AMPA receptor, ion channel, MEMBRANE PROTEIN
Deposited on 2003-04-14, released 2003-06-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-08-16, with a file datestamp of 2017-08-11.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor 2 precursor
    Species: Rattus norvegicus [TaxId:10116]
    Gene: GRIA2 OR GLUR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (119-End)
      • engineered (93)
      • insertion (117-118)
      • engineered (137)
    Domains in SCOPe 2.07: d1p1wa_
  • Chain 'B':
    Compound: Glutamate receptor 2 precursor
    Species: Rattus norvegicus [TaxId:10116]
    Gene: GRIA2 OR GLUR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (119-End)
      • engineered (93)
      • insertion (117-118)
      • engineered (137)
    Domains in SCOPe 2.07: d1p1wb_
  • Heterogens: SO4, AMQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1p1wA (A:)
ganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgk
ygardadtkiwngmvgelvygkadiaiapltityvreevidfskpfmslgisimikkgtp
iesaedlskqteiaygttdsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvar
vrkskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlk
lneqglldklknkwwydkgecgs

    Sequence, based on observed residues (ATOM records): (download) 
    >1p1wA (A:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltityvreevidfskpfmslgisimikkgtpies
aedlskqteiaygttdsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklne
qglldklknkwwydkgec

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1p1wB (B:)
ganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgk
ygardadtkiwngmvgelvygkadiaiapltityvreevidfskpfmslgisimikkgtp
iesaedlskqteiaygttdsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvar
vrkskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlk
lneqglldklknkwwydkgecgs

    Sequence, based on observed residues (ATOM records): (download) 
    >1p1wB (B:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltityvreevidfskpfmslgisimikkgtpies
aedlskqteiaygttdsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklne
qglldklknkwwydkgec