PDB entry 1orw

View 1orw on RCSB PDB site
Description: Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a Peptidomimetic Inhibitor
Class: hydrolase
Keywords: serine protease, oxyanion hole, substrate channeling, drug design, diabetes mellitus, HYDROLASE
Deposited on 2003-03-16, released 2003-05-06
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.84 Å
R-factor: 0.187
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dipeptidyl peptidase IV
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • GB AAO43404 (0-727)
    Domains in SCOPe 2.03: d1orwa1, d1orwa2
  • Chain 'B':
    Compound: dipeptidyl peptidase IV
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • GB AAO43404 (0-727)
    Domains in SCOPe 2.03: d1orwb1, d1orwb2
  • Chain 'C':
    Compound: dipeptidyl peptidase IV
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • GB AAO43404 (0-727)
    Domains in SCOPe 2.03: d1orwc1, d1orwc2
  • Chain 'D':
    Compound: dipeptidyl peptidase IV
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • GB AAO43404 (0-727)
    Domains in SCOPe 2.03: d1orwd1, d1orwd2
  • Heterogens: NAG, SO4, PHI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1orwA (A:)
srrtytltdylkstfrvkfytlqwisdheylykqennillfnaeygnssiflenstfdel
gystndysvspdrqfilfeynyvkqwrhsytasydiydlnkrqliteeripnntqwitws
pvghklayvwnndiyvknepnlssqritwtgkenviyngvtdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvripypkagaenptvkffvvdtrtlsp
nasvtsyqivppasvligdhylcgvtwvteerislqwirraqnysiidicdydestgrwi
ssvarqhieisttgwvgrfrpaephftsdgnsfykiisneegykhichfqtdksnctfit
kgawevigiealtsdylyyisnehkgmpggrnlyriqlndytkvtclscelnpercqyys
asfsnkakyyqlrcfgpglplytlhssssdkelrvlednsaldkmlqdvqmpskkldvin
lhgtkfwyqmilpphfdkskkypllievyagpcsqkvdtvfrlswatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieatrqfskmgfvddkriaiwgwsyggyvtsm
vlgagsgvfkcgiavapvskweyydsvyterymglptpednldyyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqlskalvdagvdfqtmwytdedhgiasnmahqhiythmshf
lkqcfslp

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1orwB (B:)
srrtytltdylkstfrvkfytlqwisdheylykqennillfnaeygnssiflenstfdel
gystndysvspdrqfilfeynyvkqwrhsytasydiydlnkrqliteeripnntqwitws
pvghklayvwnndiyvknepnlssqritwtgkenviyngvtdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvripypkagaenptvkffvvdtrtlsp
nasvtsyqivppasvligdhylcgvtwvteerislqwirraqnysiidicdydestgrwi
ssvarqhieisttgwvgrfrpaephftsdgnsfykiisneegykhichfqtdksnctfit
kgawevigiealtsdylyyisnehkgmpggrnlyriqlndytkvtclscelnpercqyys
asfsnkakyyqlrcfgpglplytlhssssdkelrvlednsaldkmlqdvqmpskkldvin
lhgtkfwyqmilpphfdkskkypllievyagpcsqkvdtvfrlswatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieatrqfskmgfvddkriaiwgwsyggyvtsm
vlgagsgvfkcgiavapvskweyydsvyterymglptpednldyyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqlskalvdagvdfqtmwytdedhgiasnmahqhiythmshf
lkqcfslp

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1orwC (C:)
srrtytltdylkstfrvkfytlqwisdheylykqennillfnaeygnssiflenstfdel
gystndysvspdrqfilfeynyvkqwrhsytasydiydlnkrqliteeripnntqwitws
pvghklayvwnndiyvknepnlssqritwtgkenviyngvtdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvripypkagaenptvkffvvdtrtlsp
nasvtsyqivppasvligdhylcgvtwvteerislqwirraqnysiidicdydestgrwi
ssvarqhieisttgwvgrfrpaephftsdgnsfykiisneegykhichfqtdksnctfit
kgawevigiealtsdylyyisnehkgmpggrnlyriqlndytkvtclscelnpercqyys
asfsnkakyyqlrcfgpglplytlhssssdkelrvlednsaldkmlqdvqmpskkldvin
lhgtkfwyqmilpphfdkskkypllievyagpcsqkvdtvfrlswatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieatrqfskmgfvddkriaiwgwsyggyvtsm
vlgagsgvfkcgiavapvskweyydsvyterymglptpednldyyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqlskalvdagvdfqtmwytdedhgiasnmahqhiythmshf
lkqcfslp

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1orwD (D:)
srrtytltdylkstfrvkfytlqwisdheylykqennillfnaeygnssiflenstfdel
gystndysvspdrqfilfeynyvkqwrhsytasydiydlnkrqliteeripnntqwitws
pvghklayvwnndiyvknepnlssqritwtgkenviyngvtdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvripypkagaenptvkffvvdtrtlsp
nasvtsyqivppasvligdhylcgvtwvteerislqwirraqnysiidicdydestgrwi
ssvarqhieisttgwvgrfrpaephftsdgnsfykiisneegykhichfqtdksnctfit
kgawevigiealtsdylyyisnehkgmpggrnlyriqlndytkvtclscelnpercqyys
asfsnkakyyqlrcfgpglplytlhssssdkelrvlednsaldkmlqdvqmpskkldvin
lhgtkfwyqmilpphfdkskkypllievyagpcsqkvdtvfrlswatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieatrqfskmgfvddkriaiwgwsyggyvtsm
vlgagsgvfkcgiavapvskweyydsvyterymglptpednldyyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqlskalvdagvdfqtmwytdedhgiasnmahqhiythmshf
lkqcfslp