PDB entry 1ohw

View 1ohw on RCSB PDB site
Description: 4-aminobutyrate-aminotransferase inactivated by gamma-vinyl gaba
Class: transferase
Keywords: transferase, plp-dependent enzyme, aminotransferase, 4- aminobutyric acid, antiepileptic drug target, vigabatrin pyridoxal phosphate, neurotransmitter degradation, mitochondrion, transit peptide
Deposited on 2003-06-03, released 2003-10-16
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.19
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-aminobutyrate aminotransferase
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1ohwa_
  • Chain 'B':
    Compound: 4-aminobutyrate aminotransferase
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1ohwb_
  • Chain 'C':
    Compound: 4-aminobutyrate aminotransferase
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1ohwc_
  • Chain 'D':
    Compound: 4-aminobutyrate aminotransferase
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1ohwd_
  • Heterogens: PLP, VIG, FES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ohwA (A:)
sqaaakvdvefdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdv
dgnrmldlysqissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresll
svapkgmsqlitmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdy
silsfmgafhgrtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeear
cleevedlivkyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdev
qtgggstgkfwahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsk
nlllaeviniikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdes
irnklisiarnkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladfk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ohwA (A:)
fdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdvdgnrmldlys
qissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresllsvapkgmsql
itmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdysilsfmgafh
grtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeearcleevedliv
kyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdevqtgggstgkf
wahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsknlllaevini
ikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdesirnklisiar
nkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ohwB (B:)
sqaaakvdvefdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdv
dgnrmldlysqissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresll
svapkgmsqlitmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdy
silsfmgafhgrtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeear
cleevedlivkyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdev
qtgggstgkfwahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsk
nlllaeviniikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdes
irnklisiarnkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladfk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ohwB (B:)
fdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdvdgnrmldlys
qissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresllsvapkgmsql
itmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdysilsfmgafh
grtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeearcleevedliv
kyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdevqtgggstgkf
wahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsknlllaevini
ikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdesirnklisiar
nkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1ohwC (C:)
sqaaakvdvefdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdv
dgnrmldlysqissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresll
svapkgmsqlitmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdy
silsfmgafhgrtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeear
cleevedlivkyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdev
qtgggstgkfwahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsk
nlllaeviniikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdes
irnklisiarnkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladfk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ohwC (C:)
fdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdvdgnrmldlys
qissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresllsvapkgmsql
itmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdysilsfmgafh
grtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeearcleevedliv
kyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdevqtgggstgkf
wahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsknlllaevini
ikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdesirnklisiar
nkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1ohwD (D:)
sqaaakvdvefdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdv
dgnrmldlysqissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresll
svapkgmsqlitmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdy
silsfmgafhgrtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeear
cleevedlivkyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdev
qtgggstgkfwahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsk
nlllaeviniikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdes
irnklisiarnkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladfk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ohwD (D:)
fdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdvdgnrmldlys
qissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresllsvapkgmsql
itmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdysilsfmgafh
grtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeearcleevedliv
kyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdevqtgggstgkf
wahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsknlllaevini
ikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdesirnklisiar
nkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladf