PDB entry 1lwu

View 1lwu on RCSB PDB site
Description: Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide
Class: blood clotting
Keywords: heterotrimer, protein-peptide complex, BLOOD CLOTTING
Deposited on 2002-06-03, released 2002-08-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.245
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fibrinogen alpha-1 chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02674
      • see remark 999 (71)
    Domains in SCOPe 2.07: d1lwua_
  • Chain 'B':
    Compound: fibrinogen beta chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1lwub1, d1lwub2
  • Chain 'C':
    Compound: Fibrinogen gamma chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04115
      • engineered (58)
    Domains in SCOPe 2.07: d1lwuc1, d1lwuc2
  • Chain 'D':
    Compound: Fibrinogen alpha-1 chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02674
      • see remark 999 (71)
    Domains in SCOPe 2.07: d1lwud_
  • Chain 'E':
    Compound: fibrinogen beta chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1lwue1, d1lwue2
  • Chain 'F':
    Compound: Fibrinogen gamma chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04115
      • engineered (58)
    Domains in SCOPe 2.07: d1lwuf1, d1lwuf2
  • Chain 'G':
    Compound: Fibrinogen alpha-1 chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02674
      • see remark 999 (71)
    Domains in SCOPe 2.07: d1lwug_
  • Chain 'H':
    Compound: fibrinogen beta chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1lwuh1, d1lwuh2
  • Chain 'I':
    Compound: Fibrinogen gamma chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04115
      • engineered (58)
    Domains in SCOPe 2.07: d1lwui1, d1lwui2
  • Chain 'J':
    Compound: Fibrinogen alpha-1 chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02674
      • see remark 999 (71)
    Domains in SCOPe 2.07: d1lwuj_
  • Chain 'K':
    Compound: fibrinogen beta chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1lwuk1, d1lwuk2
  • Chain 'L':
    Compound: Fibrinogen gamma chain
    Species: Petromyzon marinus [TaxId:7757]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04115
      • engineered (58)
    Domains in SCOPe 2.07: d1lwul1, d1lwul2
  • Chain 'M':
    Compound: Ligand Gly-His-Arg-Pro-NH2
    Database cross-references and differences (RAF-indexed):
    • PDB 1LWU (0-End)
  • Chain 'N':
    Compound: Ligand Gly-His-Arg-Pro-NH2
    Database cross-references and differences (RAF-indexed):
    • PDB 1LWU (0-End)
  • Chain 'O':
    Compound: Ligand Gly-His-Arg-Pro-NH2
    Database cross-references and differences (RAF-indexed):
    • PDB 1LWU (0-End)
  • Chain 'P':
    Compound: Ligand Gly-His-Arg-Pro-NH2
    Database cross-references and differences (RAF-indexed):
    • PDB 1LWU (0-End)
  • Heterogens: NH2, NDG, MAN, NAG, BMA, GAL, CA

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1lwuA (A:)
avsdtsgqtlnehnelevrysevlrelerriihlqrrinmqlqqltllqhniktqvsqil
rvevdidvalrackgscaryleyrldkeknlqlekaasyianlkferfeevvveetlnr

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuA (A:)
nelevrysevlrelerriihlqrrinmqlqqltllqhniktqvsqilrvevdidvalrac
kgscaryleyrldkeknlqlekaasyianlkferfeevv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1lwuB (B:)
ssthvnaqkeienrykevkiriestvagslrsmksvlehlrakmqrmeeaiktqkelcsa
pctvncrvpvvsgmhcediyrnggrtseayyiqpdlfsepykvfcdmeshgggwtvvqnr
vdgssnfardwntykaefgniafgngksicnipgeywlgtktvhqltkqhtqqvlfdmsd
wegssvyaqyasfrpeneaqgyrlwvedysgnagnallegatqlmgdnrtmtihngmqfs
tfdrdndnwnpgdptkhcsredaggwwynrchaanpngryywggiytkeqadygtddgvv
wmnwkgswysmrqmamklrpkwp

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuB (B:)
aqkeienrykevkiriestvagslrsmksvlehlrakmqrmeeaiktqkelcsapctvnc
rvpvvsgmhcediyrnggrtseayyiqpdlfsepykvfcdmeshgggwtvvqnrvdgssn
fardwntykaefgniafgngksicnipgeywlgtktvhqltkqhtqqvlfdmsdwegssv
yaqyasfrpeneaqgyrlwvedysgnagnallegatqlmgdnrtmtihngmqfstfdrdn
dnwnpgdptkhcsredaggwwynrchaanpngryywggiytkeqadygtddgvvwmnwkg
swysmrqmamklrpk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1lwuC (C:)
dsgqktvqkileevrileqigvshdaqiqelsemwrvnqqfvtrlqqqlvdirqtcsrpc
qdttankispitgkdcqqvvdnggkdsglyyikplkakqpflvfceiengngwtviqhrh
dgsvnftrdwvsyregfgylaptlttefwlgnekihlltgqqayrlridltdwenthrya
dyghfkltpesdeyrlfysmyldgdagnafdgfdfgddpqdkfytthlgmlfstperdnd
kyegscaeqdgsgwwmnrchaghlngkyyfggnyrktdvefpyddgiiwatwhdrwyslk
mttmkllpmgrdlsghggqqqsk

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuC (C:)
ktvqkileevrileqigvshdaqiqelsemwrvnqqfvtrlqqqlvdirqtcsrpcqdtt
ankispitgkdcqqvvdnggkdsglyyikplkakqpflvfceiengngwtviqhrhdgsv
nftrdwvsyregfgylaptlttefwlgnekihlltgqqayrlridltdwenthryadygh
fkltpesdeyrlfysmyldgdagnafdgfdfgddpqdkfytthlgmlfstperdndkyeg
scaeqdgsgwwmnrchaghlngkyyfggnyrktdvefpyddgiiwatwhdrwyslkmttm
kllpmgrdlsghggqqq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1lwuD (D:)
avsdtsgqtlnehnelevrysevlrelerriihlqrrinmqlqqltllqhniktqvsqil
rvevdidvalrackgscaryleyrldkeknlqlekaasyianlkferfeevvveetlnr

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuD (D:)
nelevrysevlrelerriihlqrrinmqlqqltllqhniktqvsqilrvevdidvalrac
kgscaryleyrldkeknlqlekaasyianlkferfeevv

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1lwuE (E:)
ssthvnaqkeienrykevkiriestvagslrsmksvlehlrakmqrmeeaiktqkelcsa
pctvncrvpvvsgmhcediyrnggrtseayyiqpdlfsepykvfcdmeshgggwtvvqnr
vdgssnfardwntykaefgniafgngksicnipgeywlgtktvhqltkqhtqqvlfdmsd
wegssvyaqyasfrpeneaqgyrlwvedysgnagnallegatqlmgdnrtmtihngmqfs
tfdrdndnwnpgdptkhcsredaggwwynrchaanpngryywggiytkeqadygtddgvv
wmnwkgswysmrqmamklrpkwp

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuE (E:)
aqkeienrykevkiriestvagslrsmksvlehlrakmqrmeeaiktqkelcsapctvnc
rvpvvsgmhcediyrnggrtseayyiqpdlfsepykvfcdmeshgggwtvvqnrvdgssn
fardwntykaefgniafgngksicnipgeywlgtktvhqltkqhtqqvlfdmsdwegssv
yaqyasfrpeneaqgyrlwvedysgnagnallegatqlmgdnrtmtihngmqfstfdrdn
dnwnpgdptkhcsredaggwwynrchaanpngryywggiytkeqadygtddgvvwmnwkg
swysmrqmamklrpk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1lwuF (F:)
dsgqktvqkileevrileqigvshdaqiqelsemwrvnqqfvtrlqqqlvdirqtcsrpc
qdttankispitgkdcqqvvdnggkdsglyyikplkakqpflvfceiengngwtviqhrh
dgsvnftrdwvsyregfgylaptlttefwlgnekihlltgqqayrlridltdwenthrya
dyghfkltpesdeyrlfysmyldgdagnafdgfdfgddpqdkfytthlgmlfstperdnd
kyegscaeqdgsgwwmnrchaghlngkyyfggnyrktdvefpyddgiiwatwhdrwyslk
mttmkllpmgrdlsghggqqqsk

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuF (F:)
ktvqkileevrileqigvshdaqiqelsemwrvnqqfvtrlqqqlvdirqtcsrpcqdtt
ankispitgkdcqqvvdnggkdsglyyikplkakqpflvfceiengngwtviqhrhdgsv
nftrdwvsyregfgylaptlttefwlgnekihlltgqqayrlridltdwenthryadygh
fkltpesdeyrlfysmyldgdagnafdgfdfgddpqdkfytthlgmlfstperdndkyeg
scaeqdgsgwwmnrchaghlngkyyfggnyrktdvefpyddgiiwatwhdrwyslkmttm
kllpmgrdlsghggqqq

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1lwuG (G:)
avsdtsgqtlnehnelevrysevlrelerriihlqrrinmqlqqltllqhniktqvsqil
rvevdidvalrackgscaryleyrldkeknlqlekaasyianlkferfeevvveetlnr

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuG (G:)
nelevrysevlrelerriihlqrrinmqlqqltllqhniktqvsqilrvevdidvalrac
kgscaryleyrldkeknlqlekaasyianlkferfeevv

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1lwuH (H:)
ssthvnaqkeienrykevkiriestvagslrsmksvlehlrakmqrmeeaiktqkelcsa
pctvncrvpvvsgmhcediyrnggrtseayyiqpdlfsepykvfcdmeshgggwtvvqnr
vdgssnfardwntykaefgniafgngksicnipgeywlgtktvhqltkqhtqqvlfdmsd
wegssvyaqyasfrpeneaqgyrlwvedysgnagnallegatqlmgdnrtmtihngmqfs
tfdrdndnwnpgdptkhcsredaggwwynrchaanpngryywggiytkeqadygtddgvv
wmnwkgswysmrqmamklrpkwp

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuH (H:)
aqkeienrykevkiriestvagslrsmksvlehlrakmqrmeeaiktqkelcsapctvnc
rvpvvsgmhcediyrnggrtseayyiqpdlfsepykvfcdmeshgggwtvvqnrvdgssn
fardwntykaefgniafgngksicnipgeywlgtktvhqltkqhtqqvlfdmsdwegssv
yaqyasfrpeneaqgyrlwvedysgnagnallegatqlmgdnrtmtihngmqfstfdrdn
dnwnpgdptkhcsredaggwwynrchaanpngryywggiytkeqadygtddgvvwmnwkg
swysmrqmamklrpk

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1lwuI (I:)
dsgqktvqkileevrileqigvshdaqiqelsemwrvnqqfvtrlqqqlvdirqtcsrpc
qdttankispitgkdcqqvvdnggkdsglyyikplkakqpflvfceiengngwtviqhrh
dgsvnftrdwvsyregfgylaptlttefwlgnekihlltgqqayrlridltdwenthrya
dyghfkltpesdeyrlfysmyldgdagnafdgfdfgddpqdkfytthlgmlfstperdnd
kyegscaeqdgsgwwmnrchaghlngkyyfggnyrktdvefpyddgiiwatwhdrwyslk
mttmkllpmgrdlsghggqqqsk

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuI (I:)
ktvqkileevrileqigvshdaqiqelsemwrvnqqfvtrlqqqlvdirqtcsrpcqdtt
ankispitgkdcqqvvdnggkdsglyyikplkakqpflvfceiengngwtviqhrhdgsv
nftrdwvsyregfgylaptlttefwlgnekihlltgqqayrlridltdwenthryadygh
fkltpesdeyrlfysmyldgdagnafdgfdfgddpqdkfytthlgmlfstperdndkyeg
scaeqdgsgwwmnrchaghlngkyyfggnyrktdvefpyddgiiwatwhdrwyslkmttm
kllpmgrdlsghg

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1lwuJ (J:)
avsdtsgqtlnehnelevrysevlrelerriihlqrrinmqlqqltllqhniktqvsqil
rvevdidvalrackgscaryleyrldkeknlqlekaasyianlkferfeevvveetlnr

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuJ (J:)
nelevrysevlrelerriihlqrrinmqlqqltllqhniktqvsqilrvevdidvalrac
kgscaryleyrldkeknlqlekaasyianlkferfeevv

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >1lwuK (K:)
ssthvnaqkeienrykevkiriestvagslrsmksvlehlrakmqrmeeaiktqkelcsa
pctvncrvpvvsgmhcediyrnggrtseayyiqpdlfsepykvfcdmeshgggwtvvqnr
vdgssnfardwntykaefgniafgngksicnipgeywlgtktvhqltkqhtqqvlfdmsd
wegssvyaqyasfrpeneaqgyrlwvedysgnagnallegatqlmgdnrtmtihngmqfs
tfdrdndnwnpgdptkhcsredaggwwynrchaanpngryywggiytkeqadygtddgvv
wmnwkgswysmrqmamklrpkwp

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuK (K:)
aqkeienrykevkiriestvagslrsmksvlehlrakmqrmeeaiktqkelcsapctvnc
rvpvvsgmhcediyrnggrtseayyiqpdlfsepykvfcdmeshgggwtvvqnrvdgssn
fardwntykaefgniafgngksicnipgeywlgtktvhqltkqhtqqvlfdmsdwegssv
yaqyasfrpeneaqgyrlwvedysgnagnallegatqlmgdnrtmtihngmqfstfdrdn
dnwnpgdptkhcsredaggwwynrchaanpngryywggiytkeqadygtddgvvwmnwkg
swysmrqmamklrpk

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1lwuL (L:)
dsgqktvqkileevrileqigvshdaqiqelsemwrvnqqfvtrlqqqlvdirqtcsrpc
qdttankispitgkdcqqvvdnggkdsglyyikplkakqpflvfceiengngwtviqhrh
dgsvnftrdwvsyregfgylaptlttefwlgnekihlltgqqayrlridltdwenthrya
dyghfkltpesdeyrlfysmyldgdagnafdgfdfgddpqdkfytthlgmlfstperdnd
kyegscaeqdgsgwwmnrchaghlngkyyfggnyrktdvefpyddgiiwatwhdrwyslk
mttmkllpmgrdlsghggqqqsk

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwuL (L:)
ktvqkileevrileqigvshdaqiqelsemwrvnqqfvtrlqqqlvdirqtcsrpcqdtt
ankispitgkdcqqvvdnggkdsglyyikplkakqpflvfceiengngwtviqhrhdgsv
nftrdwvsyregfgylaptlttefwlgnekihlltgqqayrlridltdwenthryadygh
fkltpesdeyrlfysmyldgdagnafdgfdfgddpqdkfytthlgmlfstperdndkyeg
scaeqdgsgwwmnrchaghlngkyyfggnyrktdvefpyddgiiwatwhdrwyslkmttm
kllpmgrdlsghg

  • Chain 'M':
    No sequence available.

  • Chain 'N':
    No sequence available.

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.