PDB entry 1kin

View 1kin on RCSB PDB site
Description: crystal structure of thymidine kinase from herpes simplex virus type I complexed with deoxythymidine
Class: transferase
Keywords: transferase, thymidine kinase, viridae, ds-DNA enveloped viruses, herpesviridae, alphaherpesviridae
Deposited on 1995-09-14, released 1997-03-12
The last revision prior to the SCOPe 2.08 freeze date was dated 1997-03-12, with a file datestamp of 2007-04-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.216
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidine kinase
    Species: HERPES SIMPLEX VIRUS TYPE I
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03176 (Start-363)
      • conflict (240)
      • conflict (310)
    Domains in SCOPe 2.08: d1kina_
  • Chain 'B':
    Compound: Thymidine kinase
    Species: HERPES SIMPLEX VIRUS TYPE I
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03176 (267-363)
      • conflict (240)
      • conflict (310)
    Domains in SCOPe 2.08: d1kinb_
  • Heterogens: SO4, THM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1kinA (A:)
safdqaarsrghnnrrtalrprrqqkatevrleqkmptllrvyidgphgmgkttttqllv
algsrddivyvpepmtywrvlgasetianiyttqhrldqgeisagdaavvmtsaqitmgm
pyavtdavlaphiggeagsshapppaltlifdrhpiaallcypaarylmgsmtpqavlaf
valipptlpgtnivlgalpedrhidrlakrqrpgerldlamlaairrvygllantvrylq
cggswredwgqlsgaavppqgaepqsnagprphigdtlftlfrapellapngdlynvfaw
aldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlartfar
emgean

    Sequence, based on observed residues (ATOM records): (download) 
    >1kinA (A:)
mptllrvyidgphgmgkttttqllvaldivyvpepmtywrvlgasetianiyttqhrldq
geisagdaavvmtsaqitmgmpyavtdavlaphiggeagssapppaltlifdrhpiaall
cypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerldla
mlaairrvygllantvrylqcggswredwgqlprphigdtlftlfrapellapngdlynv
fawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlart
faremge

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1kinB (B:)
safdqaarsrghnnrrtalrprrqqkatevrleqkmptllrvyidgphgmgkttttqllv
algsrddivyvpepmtywrvlgasetianiyttqhrldqgeisagdaavvmtsaqitmgm
pyavtdavlaphiggeagsshapppaltlifdrhpiaallcypaarylmgsmtpqavlaf
valipptlpgtnivlgalpedrhidrlakrqrpgerldlamlaairrvygllantvrylq
cggswredwgqlsgaavppqgaepqsnagprphigdtlftlfrapellapngdlynvfaw
aldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlartfar
emgean

    Sequence, based on observed residues (ATOM records): (download) 
    >1kinB (B:)
mptllrvyidgphgmgkttttqllvalgdivyvpepmtywrvlgasetianiyttqhrld
qgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagssapppaltlifdrhpiaal
lcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerldl
amlaairrvygllantvrylqcggswredwgqlsagprphigdtlftlfrapellapngd
lynvfawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticd
lartfaremge