PDB entry 1jr2

View 1jr2 on RCSB PDB site
Description: Structure of Uroporphyrinogen III Synthase
Class: lyase
Keywords: Heme biosynthesis, heam biosynthesis, LYASE
Deposited on 2001-08-10, released 2001-11-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-04, with a file datestamp of 2017-09-29.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: uroporphyrinogen-III synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: UROS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1jr2a_
  • Chain 'B':
    Compound: uroporphyrinogen-III synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: UROS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1jr2b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1jr2A (A:)
    mghhhhhhhhhhssghiegrhmkvlllkdakeddcgqdpyirelglygleatlipvlsfe
    flslpsfseklshpedyggliftspraveaaelcleqnnktevwerslkekwnaksvyvv
    gnataslvskigldtegetcgnaeklaeyicsressalpllfpcgnlkreilpkalkdkg
    iamesitvyqtvahpgiqgnlnsyysqqgvpasitffspsgltyslkhiqelsgdnidqi
    kfaaigpttaralaaqglpvsctaesptpqalatgirkalqphgcc
    

    Sequence, based on observed residues (ATOM records): (download)
    >1jr2A (A:)
    mkvlllkdakeddcgqdpyirelglygleatlipvlsfeflslpsfseklshpedyggli
    ftspraveaaelcleqnnktevwerslkekwnaksvyvvgnataslvskigldtegetcg
    naeklaeyicsressalpllfpcgnlkreilpkalkdkgiamesitvyqtvahpgiqgnl
    nsyysqqgvpasitffspsgltyslkhiqelsgdnidqikfaaigpttaralaaqglpvs
    ctaesptpqalatgirkalq
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1jr2B (B:)
    mghhhhhhhhhhssghiegrhmkvlllkdakeddcgqdpyirelglygleatlipvlsfe
    flslpsfseklshpedyggliftspraveaaelcleqnnktevwerslkekwnaksvyvv
    gnataslvskigldtegetcgnaeklaeyicsressalpllfpcgnlkreilpkalkdkg
    iamesitvyqtvahpgiqgnlnsyysqqgvpasitffspsgltyslkhiqelsgdnidqi
    kfaaigpttaralaaqglpvsctaesptpqalatgirkalqphgcc
    

    Sequence, based on observed residues (ATOM records): (download)
    >1jr2B (B:)
    mkvlllkdakeddcgqdpyirelglygleatlipvlsfeflslpsfseklshpedyggli
    ftspraveaaelcleqnnktevwerslkekwnaksvyvvgnataslvskigldtegetcg
    naeklaeyicsressalpllfpcgnlkreilpkalkdkgiamesitvyqtvahpgiqgnl
    nsyysqqgvpasitffspsgltyslkhiqelsgdnidqikfaaigpttaralaaqglpvs
    ctaesptpqalatgirkalq