PDB entry 1j8h

View 1j8h on RCSB PDB site
Description: Crystal Structure of a Complex of a Human alpha/beta-T cell Receptor, Influenza HA Antigen Peptide, and MHC Class II Molecule, HLA-DR4
Class: immune system
Keywords: protein-protein complex, immunoglobulin fold, IMMUNE SYSTEM
Deposited on 2001-05-21, released 2002-03-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.211
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1j8ha1, d1j8ha2
  • Chain 'B':
    Compound: hla class II histocompatibility antigen, dr-4 beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13760
      • conflict (179)
    Domains in SCOPe 2.07: d1j8hb1, d1j8hb2
  • Chain 'C':
    Compound: hemagglutinin ha1 peptide chain
    Species: Influenzavirus A [TaxId:197911]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: T-cell receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PIR RWHUAC (0-End)
    Domains in SCOPe 2.07: d1j8hd1, d1j8hd2
  • Chain 'E':
    Compound: T-cell receptor beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PIR S18894 (0-End)
      • engineered (186)
    Domains in SCOPe 2.07: d1j8he1, d1j8he2
  • Heterogens: NAG, NDG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1j8hA (A:)
    ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
    aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
    wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    d
    

    Sequence, based on observed residues (ATOM records): (download)
    >1j8hA (A:)
    keehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgala
    niavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtw
    lrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1j8hB (B:)
    gdtrprfleqvkhechffngtervrfldryfyhqeeyvrfdsdvgeyravtelgrpdaey
    wnsqkdlleqkraavdtycrhnygvgesftvqrrvypevtvypaktqplqhhnllvcsvn
    gfypgsievrwfrngqeektgvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
    tspltvewrars
    

    Sequence, based on observed residues (ATOM records): (download)
    >1j8hB (B:)
    trprfleqvkhechffngtervrfldryfyhqeeyvrfdsdvgeyravtelgrpdaeywn
    sqkdlleqkraavdtycrhnygvgesftvqrrvypevtvypanllvcsvngfypgsievr
    wfrngqeektgvvstgliqngdwtfqtlvmletvprsgevytcqvehpsvtspltvewra
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1j8hD (D:)
    qsvtqlgshvsvsegalvllrcnysssvppylfwyvqypnqglqlllkytsaatlvkgin
    gfeaefkksetsfhltkpsahmsdaaeyfcavsespfgnekltfgtgtrltiipniqnpd
    pavyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavaws
    nksdfacanafnnsiipedtffpspesscdvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1j8hD (D:)
    qsvtqlgshvsvsegalvllrcnysssvppylfwyvqypnqglqlllkytsaatlvkgin
    gfeaefkksetsfhltkpsahmsdaaeyfcavsespfgnekltfgtgtrltiipniqnpd
    pavyqlrssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnks
    dfacanafnnsiipedtf
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1j8hE (E:)
    vkvtqssrylvkrtgekvflecvqdmdhenmfwyrqdpglglrliyfsydvkmkekgdip
    egysvsrekkerfslilesastnqtsmylcassstglpygytfgsgtrltvvedlnkvfp
    pevavfepseaeishtqkatlvclatgffpdhvelswwvngkevhsgvstdpqplkeqpa
    lndsryslssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgr
    adcgft
    

    Sequence, based on observed residues (ATOM records): (download)
    >1j8hE (E:)
    vkvtqssrylvkrtgekvflecvqdmdhenmfwyrqdpglglrliyfsydvkmkekgdip
    egysvsrekkerfslilesastnqtsmylcassstglpygytfgsgtrltvvedlnkvfp
    pevavfepseaeishtqkatlvclatgffpdhvelswwvngkevhsgvstdpqplkeqpa
    lndsryslssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgr
    a