PDB entry 1iv4

View 1iv4 on RCSB PDB site
Description: Structure of 2C-Methyl-D-erythritol-2,4-cyclodiphosphate Synthase (bound form Substrate)
Class: lyase
Keywords: isoprenoid, non-mevalonate, synthase, RIKEN Structural Genomics/Proteomics Initiative, RSGI, Structural Genomics, LYASE
Deposited on 2002-03-11, released 2002-09-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: 0.202
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8RQP5
      • engineered (40)
      • engineered (80)
      • engineered (119)
    Domains in SCOPe 2.07: d1iv4a_
  • Chain 'B':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8RQP5
      • engineered (40)
      • engineered (80)
      • engineered (119)
    Domains in SCOPe 2.07: d1iv4b_
  • Chain 'C':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8RQP5
      • engineered (40)
      • engineered (80)
      • engineered (119)
    Domains in SCOPe 2.07: d1iv4c_
  • Chain 'D':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8RQP5
      • engineered (40)
      • engineered (80)
      • engineered (119)
    Domains in SCOPe 2.07: d1iv4d_
  • Chain 'E':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8RQP5
      • engineered (40)
      • engineered (80)
      • engineered (119)
    Domains in SCOPe 2.07: d1iv4e_
  • Chain 'F':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8RQP5
      • engineered (40)
      • engineered (80)
      • engineered (119)
    Domains in SCOPe 2.07: d1iv4f_
  • Heterogens: MG, C5P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1iv4A (A:)
mrigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigll
fpdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlm
rlpqdrigltfktseglapshvqaravvlldg

    Sequence, based on observed residues (ATOM records): (download) 
    >1iv4A (A:)
rigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigllf
pdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlmr
lpqdrigltfktseglapshvqaravvlld

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1iv4B (B:)
mrigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigll
fpdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlm
rlpqdrigltfktseglapshvqaravvlldg

    Sequence, based on observed residues (ATOM records): (download) 
    >1iv4B (B:)
rigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigllf
pdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlmr
lpqdrigltfktseglapshvqaravvlld

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1iv4C (C:)
mrigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigll
fpdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlm
rlpqdrigltfktseglapshvqaravvlldg

    Sequence, based on observed residues (ATOM records): (download) 
    >1iv4C (C:)
rigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigllf
pdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlmr
lpqdrigltfktseglapshvqaravvlld

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1iv4D (D:)
mrigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigll
fpdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlm
rlpqdrigltfktseglapshvqaravvlldg

    Sequence, based on observed residues (ATOM records): (download) 
    >1iv4D (D:)
rigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigllf
pdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlmr
lpqdrigltfktseglapshvqaravvlld

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1iv4E (E:)
mrigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigll
fpdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlm
rlpqdrigltfktseglapshvqaravvlldg

    Sequence, based on observed residues (ATOM records): (download) 
    >1iv4E (E:)
rigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigllf
pdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlmr
lpqdrigltfktseglapshvqaravvlld

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1iv4F (F:)
mrigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigll
fpdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlm
rlpqdrigltfktseglapshvqaravvlldg

    Sequence, based on observed residues (ATOM records): (download) 
    >1iv4F (F:)
rigygedshrleegrplylcgllipspvgalahsdgdaamhaltdallsayglgdigllf
pdtdprwrgersevflreamrlveargakllqaslvltldrpklgphrkalvdslsrlmr
lpqdrigltfktseglapshvqaravvlld