PDB entry 1itg

View 1itg on RCSB PDB site
Description: crystal structure of the catalytic domain of hiv-1 integrase: similarity to other polynucleotidyl transferases
Class: DNA integration
Keywords: DNA integration, DNA binding (viral)
Deposited on 1994-11-21, released 1995-05-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.202
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hiv-1 integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: HIV-1 INTEGRASE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12497
      • conflict (138)
    Domains in SCOPe 2.07: d1itga_
  • Heterogens: CAC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1itgA (A:)
gshmhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklag
rwpvktvhtdngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvr
dqaehlktavqmavfihnkkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >1itgA (A:)
dcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvh
tdngsnftsttvkaacwwagikqefgmnkelkkiigqvrdqaehlktavqmavfihnkkr
kggiggysagerivdiiatdiq