PDB entry 1hsi

View 1hsi on RCSB PDB site
Description: crystal structure at 1.9 angstroms resolution of human immunodeficiency virus (hiv) II protease complexed with l-735,524, an orally bioavailable inhibitor of the hiv proteases
Class: hydrolase (acid proteinase)
Keywords: hydrolase (acid proteinase)
Deposited on 1995-03-31, released 1996-04-03
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.166
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: hiv-2 protease
  Species: Human immunodeficiency virus 2 [TaxId:11709]
  Gene: HIV-2 PROTEASE FROM THE ROD ISOLATE
  Database cross-references and differences (RAF-indexed):
  • Uniprot P04584 (0-98)
  Domains in SCOPe 2.04: d1hsia_
• Chain 'B':
  Compound: hiv-2 protease
  Species: Human immunodeficiency virus 2 [TaxId:11709]
  Gene: HIV-2 PROTEASE FROM THE ROD ISOLATE
  Database cross-references and differences (RAF-indexed):
  • Uniprot P04584 (0-98)
  Domains in SCOPe 2.04: d1hsib_
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1hsiA (A:)
  pqfslwkrpvvtayiegqpvevlldtgaddsivagielgnnyspkivggiggfintkeyk
  nveievlnkkvratimtgdtpinifgrniltalgmslnl
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1hsiB (B:)
  pqfslwkrpvvtayiegqpvevlldtgaddsivagielgnnyspkivggiggfintkeyk
  nveievlnkkvratimtgdtpinifgrniltalgmslnl