PDB entry 1h19

View 1h19 on RCSB PDB site
Description: structure of [e271q] leukotriene a4 hydrolase
Class: hydrolase
Keywords: hydrolase, alpha-beta protein, leukotriene biosynthesis, metalloprotease
Deposited on 2002-07-04, released 2002-08-08
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.184
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leukotriene A-4 hydrolase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1H19
      • engineered mutation (271)
    • Uniprot P09960 (1-610)
    Domains in SCOPe 2.03: d1h19a1, d1h19a2, d1h19a3
  • Heterogens: ZN, YB, ACY, IMD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1h19A (A:)
mpeivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdl
tiekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwlt
peqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetp
dpedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetes
mlkiaedlggpyvwgqydllvlppsfpyggmqnpcltfvtptllagdkslsnviaheish
swtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfget
hpftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksi
ttddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitak
eddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwl
rlciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvt
amlvgkdlkvd

    Sequence, based on observed residues (ATOM records): (download) 
    >1h19A (A:)
peivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdlt
iekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltp
eqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpd
pedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesm
lkiaedlggpyvwgqydllvlppsfpyggmqnpcltfvtptllagdkslsnviaheishs
wtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgeth
pftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksit
tddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitake
ddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlr
lciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvta
mlvgkdlkvd