PDB entry 1fe2

View 1fe2 on RCSB PDB site
Description: crystal structure of dihomo-gamma-linoleic acid bound in the cyclooxygenase channel of prostaglandin endoperoxide h synthase-1.
Class: oxidoreductase
Keywords: Membrane Protein, Fatty Acid, Dihomo-Gamma-Linoleic Acid, Oxidoreductase, Peroxidase, Dioxygenase
Deposited on 2000-07-20, released 2001-05-02
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.237
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: prostaglandin endoperoxide h synthase-1
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • GB 165844
    Domains in SCOPe 2.03: d1fe2a1, d1fe2a2
  • Heterogens: BOG, COH, LAX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1fe2A (A:)
adpgapapvnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipeiwtwlrttlrp
spsfihfllthgrwlwdfvnatfirdtlmrlvltvrsnlipspptyniahdyiswesfsn
vsyytrilpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqgtnlmfaffaqh
fthqffktsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklkyqmlngevypp
sveeapvlmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvcdllkaehptwg
deqlfqtarliligetikivieeyvqqlsgyflqlkfdpellfgaqfqyrnriamefnql
yhwhplmpdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagrigggrnidhhi
lhvavdvikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaeleelygdidalefy
pglllekchpnsifgesmiemgapfslkgllgnpicspeywkastfggevgfnlvktatl
kklvclntktcpyvsfhvpdprqedrpgverpptel

    Sequence, based on observed residues (ATOM records): (download) 
    >1fe2A (A:)
pvnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipeiwtwlrttlrpspsfihf
llthgrwlwdfvnatfirdtlmrlvltvrsnlipspptyniahdyiswesfsnvsyytri
lpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqgtnlmfaffaqhfthqffk
tsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklkyqmlngevyppsveeapv
lmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvcdllkaehptwgdeqlfqt
arliligetikivieeyvqqlsgyflqlkfdpellfgaqfqyrnriamefnqlyhwhplm
pdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagrigggrnidhhilhvavdv
ikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaeleelygdidalefypglllek
chpnsifgesmiemgapfslkgllgnpicspeywkastfggevgfnlvktatlkklvcln
tktcpyvsfhvpd