PDB entry 1ex4

View 1ex4 on RCSB PDB site
Description: hiv-1 integrase catalytic core and c-terminal domain
Class: Viral protein
Keywords: SH3-like domain, nonspecific DNA binding beta sheet, cis-proline, Viral protein
Deposited on 2000-04-28, released 2000-06-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.258
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585
      • engineered (6)
      • engineered (81)
      • engineered (89)
      • engineered (135)
    Domains in SCOPe 2.07: d1ex4a1, d1ex4a2
  • Chain 'B':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585
      • engineered (6)
      • engineered (81)
      • engineered (135)
    Domains in SCOPe 2.07: d1ex4b1, d1ex4b2
  • Heterogens: CPS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ex4A (A:)
gsgqvdsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktihtdngsnftgatvraacdwagikqedgipynpqsqgvvesmnkelkkiigqvrdqa
ehlktavqmavfihnkkrkggiggysagerivdiiatdiqtkelqkqitkiqnfrvyyrd
srnslwkgpakllwkgegavviqdnsdikvvprrkakiirdygkqmagddsvasrqded

    Sequence, based on observed residues (ATOM records): (download) 
    >1ex4A (A:)
sspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktiht
dngsnftgatvraacdwagikqedgipqsqgvvesmnkelkkiigqvrdqaehlktavqm
avfihnkkrkggiggysagerivdiiatdiqtkelqkqitkiqnfrvyyrdsrnslwkgp
akllwkgegavviqdnsdikvvprrkakiird

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ex4B (B:)
gsgqvdsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktihtdngsnftgatvraacdwagikqedgipynpqsqgvvesmnkelkkiigqvrdqa
ehlktavqmavfihnkkrkggiggysagerivdiiatdiqtkelqkqitkiqnfrvyyrd
srnslwkgpakllwkgegavviqdnsdikvvprrkakiirdygkqmagddsvasrqded

    Sequence, based on observed residues (ATOM records): (download) 
    >1ex4B (B:)
dsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktih
tdngsnftgatvraacdwagikqvvesmnkelkkiigqvrdqaehlktavqmavfihnkk
rkggiggysagerivdiiatdiqtkelqkqitkiqnfrvyyrdsrnslwkgpakllwkge
gavviqdnsdikvvprrkakiird