PDB entry 1e8w

View 1e8w on RCSB PDB site
Description: structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine
Deposited on 2000-10-03, released 2000-11-17
The last revision prior to the SCOP 1.63 freeze date was dated 2000-11-17, with a file datestamp of 2000-11-17.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.265
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1e8wA (A:)
aseetlafqrqlnaligydvtdvsnvhddeleftrrrlvtprmaevagrdpklyamhpwv
tskplpeyllkkitnncvfivihrsttsqtikvsaddtpgtilqsfftkmakkkslmdip
esqnerdfvlrvcgrdeylvgetpiknfqwvrqclkngeeihlvldtppdpaldevrkee
wplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprtadltvf
veaniqygqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapals
gktsaempspeskgkaqllyyvnlllidhrfllrhgeyvlhmwqlsgkgedqgsfnadkl
tsatnpdkensmsisilldnychpialpkhrptpdpegdrvraempnqlrkqleaiiatd
plnpltaedkellwhfryeslkdpkaypklfssvkwgqqeivaktyqllakrevwdqsal
dvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfll
krglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqvidml
qkvtidikslsaekydvssqvisqlkqklenlqnlnlpqsfrvpydpglkagalviekck
vmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlilqilrimesiwetesldl
cllpygcistgdkigmieivkdattiakiqqstvgntgafkdevlshwlkekcpieekfq
aaverfvyscagycvatfvlgigdrhndnimisetgnlfhidfghilgnyksflginker
vpfvltpdflfvmgtsgkktslhfqkfqdvcvkaylalrhhtnlliilfsmmlmtgmpql
tskedieyirdaltvgkseedakkyfldqievcrdkgwtvqfnwflhlvlgi

    Sequence, based on observed residues (ATOM records): (download) 
    >1e8wA (A:)
aseetlafqrqlnaligydvtdvsnvhddeleftrrrlvtprmaevagrdpklyamhpwv
tskplpeyllkkitnncvfivihrsttsqtikvsaddtpgtilqsfftkmdfvlrvcgrd
eylvgetpiknfqwvrqclkngeeihlvldtppdpaldevrkevslwdcdrkfrvkirgi
dipvlprtadltvfveaniqygqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgal
lnlqiycgqllyyvnlllidhrfllrhgeyvlhmwqlsfnadkltsatnpdkensmsisi
lldnychpialpkhempnqlrkqleaiiatdplnpltaedkellwhfryeslkdpkaypk
lfssvkwgqqeivaktyqllakrevwdqsaldvgltmqlldcnfsdenvraiavqklesl
edddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqq
rfavileaylrgcgtamlhdftqqvqvidmlqkvtidikslsaekydvssqvisqlkqkl
enlqnlnlpqsfrvpydpglkagalviekckvmaskkkplwlefkcadptalsnetigii
fkhgddlrqdmlilqilrimesiwetesldlcllpygcistgdkigmieivkdattiaki
qqstvgntgafkdevlshwlkekcpieekfqaaverfvyscagycvatfvlgigdrhndn
imisetgnlfhidfgnkervpfvltpdflfvmgtsgkktslhfqkfqdvcvkaylalrhh
tnlliilfsmmlmtgmpqltskedieyirdaltvgkseedakkyfldqievcrdkgwtvq
fnwflhlvlgi