PDB entry 1bi4

View 1bi4 on RCSB PDB site
Description: catalytic domain of hiv-1 integrase
Class: DNA integration
Keywords: DNA integration, aids, polyprotein, hydrolase, endonuclease, polynucleotidyl transferase, DNA binding (viral)
Deposited on 1998-06-22, released 1998-11-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.232
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12497
      • engineered (135)
    Domains in SCOPe 2.07: d1bi4a_
  • Chain 'B':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12497 (Start-159)
      • conflict (100)
      • engineered (135)
    Domains in SCOPe 2.07: d1bi4b_
  • Chain 'C':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12497 (0-159)
      • engineered (135)
    Domains in SCOPe 2.07: d1bi4c_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1bi4A (A:)
mhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvrdqa
ehlktavqmavfihnhkrkggiggysagerivdiiatdiq

    Sequence, based on observed residues (ATOM records): (download) 
    >1bi4A (A:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacwwagikqefgiesmnkelkkiigqvrdqaehlktavqmavfihnhk
rkggiggysagerivdiiatdi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1bi4B (B:)
mhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsttvkaacwwagikqefgipynpqsqgliesmnkelkkiigqvrdqa
ehlktavqmavfihnhkrkggiggysagerivdiiatdiq

    Sequence, based on observed residues (ATOM records): (download) 
    >1bi4B (B:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacwwagikqefliesmnkelkkiigqvrdqaehlktavqmavfihnhk
rkggiggysagerivdiiatdiq

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1bi4C (C:)
mhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvrdqa
ehlktavqmavfihnhkrkggiggysagerivdiiatdiq