SCOP 1.75: Domain d1rpna_: 1rpn A:

Lineage for d1rpna_ (1rpn A:)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein GDP-mannose 4,6-dehydratase [51759] (4 species)

7. Species Pseudomonas aeruginosa [TaxId:287] [102134] (1 PDB entry)

8. Domain d1rpna_: 1rpn A: [97708]

Details for d1rpna_

PDB Entry: 1rpn, 2.15 Å

PDB Description: Crystal Structure of GDP-D-mannose 4,6-dehydratase in complexes with GDP and NADPH

PDB Compounds: (A:) GDP-mannose 4,6-dehydratase

SCOP Domain Sequences for d1rpna_:

Sequence; same for both SEQRES and ATOM records:

>d1rpna_ c.2.1.2 (A:) GDP-mannose 4,6-dehydratase {Pseudomonas aeruginosa [TaxId: 287]}
rsalvtgitgqdgaylaklllekgyrvhglvarrssdtrwrlrelgiegdiqyedgdmad
acsvqravikaqpqevynlaaqsfvgaswnqpvttgvvdglgvthlleairqfspetrfy
qastsemfgliqaerqdentpfyprspygvaklyghwitvnyresfglhassgilfnhes
plrgiefvtrkvtdavariklgkqqelrlgnvdakrdwgfagdyveamwlmlqqdkaddy
vvatgvtttvrdmcqiafehvgldyrdflkidpaffrpaevdvllgnpakaqrvlgwkpr
tsldelirmmveadlrrvsre

Timeline for d1rpna_:

• d1rpna_ first appeared in SCOP 1.67
  
• d1rpna_ appears in SCOP 1.73
  
• d1rpna_ appears in SCOPe 2.01
  
• d1rpna_ appears in the current release, SCOPe 2.08