Lineage for d1r2ia_ (1r2i A:)

  1. Root: SCOP 1.69
  2. 519077Class f: Membrane and cell surface proteins and peptides [56835] (47 folds)
  3. 519078Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 519118Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (1 family) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 519119Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (8 proteins)
  6. 519124Protein Apoptosis regulator Bcl-xL [56856] (3 species)
  7. 519125Species Human (Homo sapiens) [TaxId:9606] [56857] (9 PDB entries)
  8. 519127Domain d1r2ia_: 1r2i A: [96868]

Details for d1r2ia_

PDB Entry: 1r2i (more details), 2 Å

PDB Description: human bcl-xl containing a phe to leu mutation at position 146

SCOP Domain Sequences for d1r2ia_:

Sequence, based on SEQRES records: (download)

>d1r2ia_ f.1.4.1 (A:) Apoptosis regulator Bcl-xL {Human (Homo sapiens)}
msqsnrelvvdflsyklsqkgyswsqfsdveenrteapegtesemetpsaingnpswhla
dspavngatghsssldarevipmaavkqalreagdefelryrrafsdltsqlhitpgtay
qsfeqvvnelfrdgvnwgrivaffslggalcvesvdkemqvlvsriaawmatylndhlep
wiqenggwdtfvelygn

Sequence, based on observed residues (ATOM records): (download)

>d1r2ia_ f.1.4.1 (A:) Apoptosis regulator Bcl-xL {Human (Homo sapiens)}
msqsnrelvvdflsyklsqkgyswsqfpmaavkqalreagdefelryrrafsdltsqlhi
tpgtayqsfeqvvnelfrdgvnwgrivaffslggalcvesvdkemqvlvsriaawmatyl
ndhlepwiqenggwdtfvelygn

SCOP Domain Coordinates for d1r2ia_:

Click to download the PDB-style file with coordinates for d1r2ia_.
(The format of our PDB-style files is described here.)

Timeline for d1r2ia_: