SCOP 1.67: Domain d1p57b_: 1p57 B:

Lineage for d1p57b_ (1p57 B:)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (44 proteins)

6. Protein Hepsin, catalytic domain [101813] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101814] (1 PDB entry)

8. Domain d1p57b_: 1p57 B: [94126]
   Other proteins in same PDB: d1p57a_
   complexed with cr4; mutant

Details for d1p57b_

PDB Entry: 1p57, 1.75 Å

PDB Description: extracellular domain of human hepsin

SCOP Domain Sequences for d1p57b_:

Sequence, based on SEQRES records:

>d1p57b_ b.47.1.2 (B:) Hepsin, catalytic domain {Human (Homo sapiens)}
ivggrdtslgrwpwqvslrydgahlcggsllsgdwvltaahcfpernrvlsrwrvfagav
aqasphglqlgvqavvyhggylpfrdpnseensndialvhlssplplteyiqpvclpaag
qalvdgkictvtgwgntqyygqqagvlqearvpiisndvcngadfygnqikpkmfcagyp
eggidacqgdsggpfvcedsisrtprwrlcgivswgtgcalaqkpgvytkvsdfrewifq
aikthseasgmvtq

Sequence, based on observed residues (ATOM records):

>d1p57b_ b.47.1.2 (B:) Hepsin, catalytic domain {Human (Homo sapiens)}
ivggrdtslgrwpwqvslrydgahlcggsllsgdwvltaahcfpernrvlsrwrvfagav
aqasphglqlgvqavvyhggylpfnsndialvhlssplplteyiqpvclpaagqalvdgk
ictvtgwgntqyygqqagvlqearvpiisndvcngadfygnqikpkmfcagypeggidac
qgdsggpfvcedsisrtprwrlcgivswgtgcalaqkpgvytkvsdfrewifqaikthse
asgmvtq

Timeline for d1p57b_:

• d1p57b_ is new in SCOP 1.67
  
• d1p57b_ appears in SCOP 1.69
  
• d1p57b_ appears in the current release, SCOPe 2.08