SCOP 1.75: Domain d1o7ac1: 1o7a C:200-554

Lineage for d1o7ac1 (1o7a C:200-554)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (14 families)

5. Family c.1.8.6: beta-N-acetylhexosaminidase catalytic domain [51550] (5 proteins)
   Glycosyl hydrolase family 20, GH20

6. Protein beta-hexosaminidase B [89486] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89487] (6 PDB entries)

8. Domain d1o7ac1: 1o7a C:200-554 [92612]
   Other proteins in same PDB: d1o7aa2, d1o7ab2, d1o7ac2, d1o7ad2, d1o7ae2, d1o7af2

Details for d1o7ac1

PDB Entry: 1o7a, 2.25 Å

PDB Description: human beta-hexosaminidase b

PDB Compounds: (C:) beta-hexosaminidase beta chain

SCOP Domain Sequences for d1o7ac1:

Sequence, based on SEQRES records:

>d1o7ac1 c.1.8.6 (C:200-554) beta-hexosaminidase B {Human (Homo sapiens) [TaxId: 9606]}
fshrgilidtsrhylpvkiilktldamafnkfnvlhwhivddqsfpyqsitfpelsnkgs
yslshvytpndvrmvieyarlrgirvlpefdtpghtlswgkgqkdlltpcysrqnkldsf
gpinptlnttysflttffkeisevfpdqfihlggdevefkcwesnpkiqdfmrqkgfgtd
fkklesfyiqkvldiiatinkgsivwqevfddkaklapgtivevwkdsaypeelsrvtas
gfpvilsapwyldlisygqdwrkyykvepldfggtqkqkqlfiggeaclwgeyvdatnlt
prlwprasavgerlwsskdvrdmddaydrltrhrcrmvergiaaqplyagycnhe

Sequence, based on observed residues (ATOM records):

>d1o7ac1 c.1.8.6 (C:200-554) beta-hexosaminidase B {Human (Homo sapiens) [TaxId: 9606]}
fshrgilidtsrhylpvkiilktldamafnkfnvlhwhivddqsfpyqsitfpelsnkgs
yslshvytpndvrmvieyarlrgirvlpefdtpghtlswgkgqkdlltpcyskldsfgpi
nptlnttysflttffkeisevfpdqfihlggdevefkcwesnpkiqdfmrqkgfgtdfkk
lesfyiqkvldiiatinkgsivwqevfddkaklapgtivevwkdsaypeelsrvtasgfp
vilsapwyldlisygqdwrkyykvepldfggtqkqkqlfiggeaclwgeyvdatnltprl
wprasavgerlwsskdvrdmddaydrltrhrcrmvergiaaqplyagycnhe

Timeline for d1o7ac1:

• d1o7ac1 first appeared in SCOP 1.67
  
• d1o7ac1 appears in SCOP 1.73
  
• d1o7ac1 appears in SCOPe 2.01
  
• d1o7ac1 appears in the current release, SCOPe 2.08