SCOPe 2.01: Family c.50.1.2: Macro domain

Lineage for Family c.50.1.2: Macro domain

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.50: Macro domain-like [52948] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 6 strands, order 165243, strand 3 is antiparallel to the rest

4. Superfamily c.50.1: Macro domain-like [52949] (3 families)

5. Family c.50.1.2: Macro domain [89724] (7 proteins)
   found in different proteins, including macro-H2a histone and the Appr-1"-p processing enzyme

Proteins:

1. Histone macro-H2a1.1 [142547] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [142549] (3 PDB entries)
      Uniprot O75367 179-367! Uniprot O75367 181-371

   2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [142548] (1 PDB entry)
      Uniprot Q02874 180-370

2. Hypothetical protein AF1521 [89725] (1 species)
   contains extra N-terminal strand

   • Species Archaeoglobus fulgidus [TaxId:2234] [89726] (4 PDB entries)
     Uniprot O28751

3. Hypothetical protein BT1257 [142545] (1 species)

   • Species Bacteroides thetaiotaomicron [TaxId:818] [142546] (1 PDB entry)
     Uniprot Q8A8B0 2-155

4. Hypothetical protein YmbD [102530] (1 species)

   • Species Escherichia coli [TaxId:562] [102531] (1 PDB entry)

5. Hypothetical protein Ymr087W [110654] (1 species)
   contains structural variations at both termini

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [110655] (3 PDB entries)
     Uniprot Q04299

6. Replicase polyprotein 1ab [142550] (1 species)

   • Species SARS coronavirus [TaxId:227859] [142551] (1 PDB entry)
     Uniprot P59641 1002-1169

7. automated matches [190472] (4 species)
   not a true protein

   1. Species Bacteroides thetaiotaomicron [TaxId:226186] [187703] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [189352] (1 PDB entry)

   3. Species Sars coronavirus tor2 [TaxId:227984] [187392] (1 PDB entry)

   4. Species SARS coronavirus [TaxId:227859] [187695] (1 PDB entry)

More info for Family c.50.1.2: Macro domain

Timeline for Family c.50.1.2: Macro domain:

• Family c.50.1.2: Macro domain first appeared in SCOP 1.65
  
• Family c.50.1.2: Macro domain appears in SCOP 1.75
  
• Family c.50.1.2: Macro domain appears in SCOPe 2.02
  
• Family c.50.1.2: Macro domain appears in the current release, SCOPe 2.08