Lineage for Species: Human (Homo sapiens)

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 312976Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 312977Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 313058Family c.36.1.7: Branched-chain alpha-keto acid dehydrogenase Pyr module [88741] (4 proteins)
    parent family to TK and PFOR
    heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
  6. 313065Protein E1-beta subunit of pyruvate dehydrogenase (PP module) [89651] (1 species)
  7. 313066Species Human (Homo sapiens) [TaxId:9606] [89652] (1 PDB entry)

PDB entry in Species: Human (Homo sapiens):

More info for Species Human (Homo sapiens) [TaxId:9606] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase (PP module)

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase (PP module):

  • Species Human (Homo sapiens) [TaxId:9606] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase (PP module) is new in SCOP 1.65
  • Species Human (Homo sapiens) [TaxId:9606] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase (PP module) is called Species Human (Homo sapiens) [TaxId:9606] from c.36.1.11 E1-beta subunit of pyruvate dehydrogenase (PP module) in SCOP 1.67
  • Species Human (Homo sapiens) [TaxId:9606] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase (PP module) appears in the current release, SCOPe 2.07, called Species Human (Homo sapiens) [TaxId:9606] from c.36.1.11 E1-beta subunit of pyruvate dehydrogenase (PP module)