SCOP 1.65: Domain d1oyt.1: 1oyt L:,H:

Lineage for d1oyt.1 (1oyt L:,H:)

1. Root: SCOP 1.65

2. Class b: All beta proteins [48724] (126 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (43 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (137 PDB entries)

8. Domain d1oyt.1: 1oyt L:,H: [87615]
   complexed with ca, fsn, na, sin

Details for d1oyt.1

PDB Entry: 1oyt, 1.67 Å

PDB Description: complex of recombinant human thrombin with a designed fluorinated inhibitor

SCOP Domain Sequences for d1oyt.1:

Sequence, based on SEQRES records:

>g1oyt.1 b.47.1.2 (L:,H:) Thrombin {Human (Homo sapiens)}
adcglrplfekksledkterellesyiXivegsdaeigmspwqvmlfrkspqellcgasl
isdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynw
renldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtanv
gkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmk
spfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqf

Sequence, based on observed residues (ATOM records):

>g1oyt.1 b.47.1.2 (L:,H:) Thrombin {Human (Homo sapiens)}
adcglrplfekksledkterellesyiXivegsdaeigmspwqvmlfrkspqellcgasl
isdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynw
renldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketgqpsv
lqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrw
yqmgivswgegcdrdgkygfythvfrlkkwiqkvidqf

Timeline for d1oyt.1:

• d1oyt.1 is new in SCOP 1.65
  
• d1oyt.1 appears in SCOP 1.67
  
• d1oyt.1 appears in the current release, SCOPe 2.08