Lineage for d1obha3 (1obh A:1-225,A:418-686)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2105373Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
    core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145
  4. 2105374Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families) (S)
  5. 2105375Family c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (13 protein domains)
    contains a conserved all-alpha subdomain at the C-terminal extension
  6. 2105449Protein Leucyl-tRNA synthetase (LeuRS) [82356] (1 species)
  7. 2105450Species Thermus thermophilus [TaxId:274] [82357] (3 PDB entries)
    contains a non-conserved insertion (residues 581-633) that forms a separate subdomain; possible rudiment Zn finger
  8. 2105453Domain d1obha3: 1obh A:1-225,A:418-686 [86775]
    Other proteins in same PDB: d1obha1, d1obha2
    protein/RNA complex; complexed with hg, lms, nva, so4

Details for d1obha3

PDB Entry: 1obh (more details), 2.2 Å

PDB Description: leucyl-trna synthetase from thermus thermophilus complexed with a pre-transfer editing substrate analogue in both synthetic active site and editing site
PDB Compounds: (A:) leucyl-tRNA synthetase

SCOPe Domain Sequences for d1obha3:

Sequence, based on SEQRES records: (download)

>d1obha3 c.26.1.1 (A:1-225,A:418-686) Leucyl-tRNA synthetase (LeuRS) {Thermus thermophilus [TaxId: 274]}
mekynphaieakwqrfweekgfmkakdlpggrgkqyvlvmfpypsgdlhmghlknytmgd
vlarfrrmqgyevlhpmgwdafglpaenaalkfgvhpkdwtyanirqakeslrlmgilyd
wdrevttcepeyyrwnqwiflkmwekglayrakglvnwcpkcqtvlaneqvvegrcwrhe
dtpvekreleqwylritayaerllkdleglnwpekvkamqrawigXrlrdwlisrqrywg
tpipmvhceacgvvpvpeeelpvllpdlkdvedirpkgkspleahpefyettcpkcggpa
krdtdtmdtffdsswyylrytdphndrlpfdpekanawmpvdqyiggvehavlhllysrf
ftkflhdlgmvkveepfqglftqgmvlawtdfgpvevegsvvrlpeptrirleipesals
ledvrkmgaelrphedgtlhlwkpavmskskgngvmvgpfvkeqgadiaritilfaappe
nemvwteegvqgawr

Sequence, based on observed residues (ATOM records): (download)

>d1obha3 c.26.1.1 (A:1-225,A:418-686) Leucyl-tRNA synthetase (LeuRS) {Thermus thermophilus [TaxId: 274]}
mekynphaieakwqrfweekgfmkakdlpgggkqyvlvmfpypsgdlhmghlknytmgdv
larfrrmqgyevlhpmgwdafglpaenaalkfgvhpkdwtyanirqakeslrlmgilydw
drevttcepeyyrwnqwiflkmwekglayrakeqwylritayaerllkdleglnwpekvk
amqrawigXrlrdwlisrqrywgtpipmvhcvvpvpeeelpvllpdlkdvedispleahp
efyettcpkrdtdtmdtffdsswyylrytdphndrlpfdpekanawmpvdqyiggvehav
lhllysrfftkflhdlgmvkveepfqglftqgmvlawtdfgpvevegsvvrlpeptrirl
eipesalsledvrkmgaelrphedgtlhlwkpavmskskgngvmvgpfvkeqgadiarit
ilfaappenemvwteegvqgawr

SCOPe Domain Coordinates for d1obha3:

Click to download the PDB-style file with coordinates for d1obha3.
(The format of our PDB-style files is described here.)

Timeline for d1obha3: