SCOP 1.71: Domain d1nysb_: 1nys B:

Lineage for d1nysb_ (1nys B:)

1. Root: SCOP 1.71

2. Class g: Small proteins [56992] (79 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (7 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (7 proteins)

6. Protein Activin A (Inhibin beta A) [90170] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [90171] (3 PDB entries)

8. Domain d1nysb_: 1nys B: [86414]
   Other proteins in same PDB: d1nysa_, d1nysc_

Details for d1nysb_

PDB Entry: 1nys, 3.05 Å

PDB Description: crystal structure of activin a bound to the ecd of actriib p41

SCOP Domain Sequences for d1nysb_:

Sequence, based on SEQRES records:

>d1nysb_ g.17.1.2 (B:) Activin A (Inhibin beta A) {Human (Homo sapiens)}
lecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhst
vinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

Sequence, based on observed residues (ATOM records):

>d1nysb_ g.17.1.2 (B:) Activin A (Inhibin beta A) {Human (Homo sapiens)}
lecdgnicckkqffvsfkdigwndwiiapsgyhanycegecpshilksccvptklrpmsm
lyyddgqniikkdiqnmiveecgcs

Timeline for d1nysb_:

• d1nysb_ first appeared in SCOP 1.65
  
• d1nysb_ appears in SCOP 1.69
  
• d1nysb_ appears in SCOP 1.73
  
• d1nysb_ appears in the current release, SCOPe 2.08