SCOP 1.67: Domain d1n25b_: 1n25 B:

Lineage for d1n25b_ (1n25 B:)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (22 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.20: Extended AAA-ATPase domain [81269] (18 proteins)
   fold is similar to that of RecA, but lacks the last two strands, followed by a family-specific Arg-finger domain

6. Protein Papillomavirus large T antigen helicase domain [89688] (1 species)

7. Species Simian virus 40 [TaxId:10633] [89689] (1 PDB entry)

8. Domain d1n25b_: 1n25 B: [85265]
   complexed with zn

Details for d1n25b_

PDB Entry: 1n25, 2.8 Å

PDB Description: Crystal structure of the SV40 Large T antigen helicase domain

SCOP Domain Sequences for d1n25b_:

Sequence; same for both SEQRES and ATOM records:

>d1n25b_ c.37.1.20 (B:) Papillomavirus large T antigen helicase domain {Simian virus 40}
kqvswklvteyametkcddvllllgmylefqysfemclkcikkeqpshykyhekhyanaa
ifadsknqkticqqavdtvlakkrvdslqltreqmltnrfndlldrmdimfgstgsadie
ewmagvawlhcllpkmdsvvydflkcmvynipkkrywlfkgpidsgkttlaaallelcgg
kalnvnlpldrlnfelgvaidqflvvfedvkgtggesrdlpsgqginnldnlrdyldgsv
kvnlekkhlnkrtqifppgivtmneysvpktlqarfvkqidfrpkdylkhclerseflle
kriiqsgialllmliwyrpvaefaqsiqsrivewkerldkefslsvyqkmkfnvamgigv
ld

Timeline for d1n25b_:

• d1n25b_ first appeared in SCOP 1.65
  
• d1n25b_ appears in SCOP 1.69
  
• d1n25b_ appears in the current release, SCOPe 2.08