SCOPe 2.06: Family a.77.1.4: DEATH effector domain, DED

Lineage for Family a.77.1.4: DEATH effector domain, DED

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.77: DEATH domain [47985] (1 superfamily)
   6 helices: closed bundle; greek-key; internal pseudo twofold symmetry

4. Superfamily a.77.1: DEATH domain [47986] (5 families)

5. Family a.77.1.4: DEATH effector domain, DED [81388] (2 proteins)

Proteins:

1. FADD (Mort1) [81387] (1 species)
   contains two domains of this superfamily: DED and DD, in this order

   • Species Human (Homo sapiens) [TaxId:9606] [81386] (3 PDB entries)

2. PEA-15 (phosphoprotein enriched in astrocytes 15 kDa) [81818] (1 species)
   DED is followed by an irregular C-terminal tail

   • Species Chinese hamster (Cricetulus griseus) [TaxId:10029] [81819] (1 PDB entry)

More info for Family a.77.1.4: DEATH effector domain, DED

Timeline for Family a.77.1.4: DEATH effector domain, DED:

• Family a.77.1.4: DEATH effector domain, DED first appeared in SCOP 1.63
  
• Family a.77.1.4: DEATH effector domain, DED appears in SCOPe 2.05
  
• Family a.77.1.4: DEATH effector domain, DED appears in SCOPe 2.07
  
• Family a.77.1.4: DEATH effector domain, DED appears in the current release, SCOPe 2.08