SCOP 1.67: Domain d1mu7a2: 1mu7 A:351-608

Lineage for d1mu7a2 (1mu7 A:351-608)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.136: Phospholipase D/nuclease [56023] (1 superfamily)
   beta-alpha-beta-alpha-beta-alpha-beta(4)-alpha; mixed sheet: order 1765234

4. Superfamily d.136.1: Phospholipase D/nuclease [56024] (3 families)

5. Family d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1 [69815] (1 protein)

6. Protein Tyrosyl-DNA phosphodiesterase TDP1 [69816] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69817] (12 PDB entries)

8. Domain d1mu7a2: 1mu7 A:351-608 [79476]

Details for d1mu7a2

PDB Entry: 1mu7, 2 Å

PDB Description: crystal structure of a human tyrosyl-dna phosphodiesterase (tdp1)- tungstate complex

SCOP Domain Sequences for d1mu7a2:

Sequence, based on SEQRES records:

>d1mu7a2 d.136.1.3 (A:351-608) Tyrosyl-DNA phosphodiesterase TDP1 {Human (Homo sapiens)}
nvyligstpgrfqgsqkdnwghfrlkkllkdhassmpnaeswpvvgqfssvgslgadesk
wlcsefkesmltlgkesktpgkssvplyliypsvenvrtslegypaggslpysiqtaekq
nwlhsyfhkwsaetsgrsnamphiktymrpspdfskiawflvtsanlskaawgalekngt
qlmirsyelgvlflpsalgldsfkvkqkffagsqepmatfpvpydlppelygskdrpwiw
nipyvkapdthgnmwvps

Sequence, based on observed residues (ATOM records):

>d1mu7a2 d.136.1.3 (A:351-608) Tyrosyl-DNA phosphodiesterase TDP1 {Human (Homo sapiens)}
nvyligstpgrfqgsqkdnwghfrlkkllkdhaaeswpvvgqfssvgslgadeskwlcse
fkesmltlgsvplyliypsvenvrtslegypaggslpysiqtaekqnwlhsyfhkwsaet
sgrsnamphiktymrpspdfskiawflvtsanlskaawgaletqlmirsyelgvlflpsa
lgldsfkvkqkfatfpvpydlppelygskdrpwiwnipyvkapdthgnmwvps

Timeline for d1mu7a2:

• d1mu7a2 first appeared in SCOP 1.63
  
• d1mu7a2 appears in SCOP 1.65
  
• d1mu7a2 appears in SCOP 1.69
  
• d1mu7a2 appears in the current release, SCOPe 2.08