SCOP 1.67: Protein: Tyrosyl-DNA phosphodiesterase TDP1

Lineage for Protein: Tyrosyl-DNA phosphodiesterase TDP1

Root: SCOP 1.67
Class d: Alpha and beta proteins (a+b) [53931] (260 folds)
Fold d.136: Phospholipase D/nuclease [56023] (1 superfamily)
beta-alpha-beta-alpha-beta-alpha-beta(4)-alpha; mixed sheet: order 1765234
Superfamily d.136.1: Phospholipase D/nuclease [56024] (3 families)
Family d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1 [69815] (1 protein)
Protein Tyrosyl-DNA phosphodiesterase TDP1 [69816] (1 species)

Species:

Human (Homo sapiens) [TaxId:9606] [69817] (12 PDB entries)
1. Domains for 1jy1:
  1. Domain d1jy1a1: 1jy1 A:145-350 [67438]
  2. Domain d1jy1a2: 1jy1 A:351-608 [67439]
2. Domains for 1mu7:
  1. Domain d1mu7a1: 1mu7 A:162-350 [79475]
  2. Domain d1mu7a2: 1mu7 A:351-608 [79476]
  3. Domain d1mu7b1: 1mu7 B:158-350 [79477]
  4. Domain d1mu7b2: 1mu7 B:351-608 [79478]
    complexed with gol, wo4; mutant
3. Domains for 1mu9:
  1. Domain d1mu9a1: 1mu9 A:162-350 [79479]
  2. Domain d1mu9a2: 1mu9 A:351-608 [79480]
  3. Domain d1mu9b1: 1mu9 B:159-350 [79481]
  4. Domain d1mu9b2: 1mu9 B:351-608 [79482]
    complexed with gol, vo4; mutant
4. Domains for 1nop:
  1. Domain d1nopa1: 1nop A:162-350 [85928]
  2. Domain d1nopa2: 1nop A:351-608 [85929]
  3. Domain d1nopb1: 1nop B:159-350 [85930]
  4. Domain d1nopb2: 1nop B:351-607 [85931]
    complexed with a topoisomerase I-derived peptide, chain C
    complexed with vo4; mutant
5. Domains for 1qzq:
  1. Domain d1qzqa1: 1qzq A:161-350 [96655]
  2. Domain d1qzqa2: 1qzq A:351-608 [96656]
  3. Domain d1qzqb1: 1qzq B:161-350 [96657]
  4. Domain d1qzqb2: 1qzq B:351-608 [96658]
6. Domains for 1rff:
  1. Domain d1rffa1: 1rff A:162-350 [97376]
  2. Domain d1rffa2: 1rff A:351-608 [97377]
  3. Domain d1rffb1: 1rff B:162-350 [97378]
  4. Domain d1rffb2: 1rff B:351-607 [97379]
    complexed with spm, vo4; mutant
7. Domains for 1rfi:
  1. Domain d1rfia1: 1rfi A:162-350 [97380]
  2. Domain d1rfia2: 1rfi A:351-608 [97381]
  3. Domain d1rfib1: 1rfi B:162-350 [97382]
  4. Domain d1rfib2: 1rfi B:351-607 [97383]
    complexed with spm, vo4; mutant
8. Domains for 1rg1:
  1. Domain d1rg1a1: 1rg1 A:162-350 [97415]
  2. Domain d1rg1a2: 1rg1 A:351-608 [97416]
  3. Domain d1rg1b1: 1rg1 B:162-350 [97417]
  4. Domain d1rg1b2: 1rg1 B:351-607 [97418]
    complexed with ots, spm, vo4; mutant
9. Domains for 1rg2:
  1. Domain d1rg2a1: 1rg2 A:162-350 [97419]
  2. Domain d1rg2a2: 1rg2 A:351-608 [97420]
  3. Domain d1rg2b1: 1rg2 B:159-350 [97421]
  4. Domain d1rg2b2: 1rg2 B:351-608 [97422]
    complexed with otr, ots, spm, vo4; mutant
10. Domains for 1rgt:
  1. Domain d1rgta1: 1rgt A:162-350 [97446]
  2. Domain d1rgta2: 1rgt A:351-608 [97447]
  3. Domain d1rgtb1: 1rgt B:162-350 [97448]
  4. Domain d1rgtb2: 1rgt B:351-607 [97449]
    complexed with otr, ots, spm, vo4; mutant
11. Domains for 1rgu:
  1. Domain d1rgua1: 1rgu A:162-350 [97450]
  2. Domain d1rgua2: 1rgu A:351-608 [97451]
  3. Domain d1rgub1: 1rgu B:162-350 [97452]
  4. Domain d1rgub2: 1rgu B:351-607 [97453]
    complexed with ots, spm, vo4; mutant
12. Domains for 1rh0:
  1. Domain d1rh0a1: 1rh0 A:162-350 [97458]
  2. Domain d1rh0a2: 1rh0 A:351-608 [97459]
  3. Domain d1rh0b1: 1rh0 B:162-350 [97460]
  4. Domain d1rh0b2: 1rh0 B:351-607 [97461]
    complexed with ots, spm, vo4; mutant

More info for Protein Tyrosyl-DNA phosphodiesterase TDP1 from d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1

Timeline for Protein Tyrosyl-DNA phosphodiesterase TDP1 from d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1:

Protein Tyrosyl-DNA phosphodiesterase TDP1 from d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1 first appeared in SCOP 1.59
Protein Tyrosyl-DNA phosphodiesterase TDP1 from d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1 appears in SCOP 1.65
Protein Tyrosyl-DNA phosphodiesterase TDP1 from d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1 appears in SCOP 1.69
Protein Tyrosyl-DNA phosphodiesterase TDP1 from d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1 appears in the current release, SCOPe 2.08