Lineage for d1mhw.1 (1mhw A:,C:)

  1. Root: SCOP 1.69
  2. 496776Class d: Alpha and beta proteins (a+b) [53931] (279 folds)
  3. 498098Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 498099Superfamily d.3.1: Cysteine proteinases [54001] (11 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 498100Family d.3.1.1: Papain-like [54002] (23 proteins)
  6. 498151Protein (Pro)cathepsin L [54026] (1 species)
  7. 498152Species Human (Homo sapiens) [TaxId:9606] [54027] (4 PDB entries)
  8. 498154Domain d1mhw.1: 1mhw A:,C: [79132]

Details for d1mhw.1

PDB Entry: 1mhw (more details), 1.9 Å

PDB Description: design of non-covalent inhibitors of human cathepsin l. from the 96- residue proregion to optimized tripeptides

SCOP Domain Sequences for d1mhw.1:

Sequence; same for both SEQRES and ATOM records: (download)

>g1mhw.1 d.3.1.1 (A:,C:) (Pro)cathepsin L {Human (Homo sapiens)}
aprsvdwrekgyvtpvknqgqcgscwafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandtgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfepdcssedmdhgvlvvgygfesXnkywl
vknswgeewgmggyvkmakdrrnhcgiasaasyptv

SCOP Domain Coordinates for d1mhw.1:

Click to download the PDB-style file with coordinates for d1mhw.1.
(The format of our PDB-style files is described here.)

Timeline for d1mhw.1: