SCOPe 2.08: Domain d1h27d1: 1h27 D:175-309

Lineage for d1h27d1 (1h27 D:175-309)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.74: Cyclin-like [47953] (1 superfamily)
   core: 5 helices; one helix is surrounded by the others

4. Superfamily a.74.1: Cyclin-like [47954] (4 families)
   duplication: consists of two domains of this fold

5. Family a.74.1.1: Cyclin [47955] (9 proteins)

6. Protein Cyclin A [47956] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47957] (89 PDB entries)
   Uniprot P20248 175-432

8. Domain d1h27d1: 1h27 D:175-309 [76538]
   Other proteins in same PDB: d1h27a1, d1h27a2, d1h27c1, d1h27c2

Details for d1h27d1

PDB Entry: 1h27, 2.2 Å

PDB Description: cdk2/cyclin a in complex with an 11-residue recruitment peptide from p27

PDB Compounds: (D:) cyclin a2

SCOPe Domain Sequences for d1h27d1:

Sequence, based on SEQRES records:

>d1h27d1 a.74.1.1 (D:175-309) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}
evpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlh
lavnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlr
mehlvlkvltfdlaap

Sequence, based on observed residues (ATOM records):

>d1h27d1 a.74.1.1 (D:175-309) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}
vpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhl
avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrm
ehlvlkvltfdlaap

Timeline for d1h27d1:

• d1h27d1 first appeared in SCOP 1.63
  
• d1h27d1 appears in SCOPe 2.07