SCOPe 2.08: Family c.10.2.7: Ngr ectodomain-like

Lineage for Family c.10.2.7: Ngr ectodomain-like

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.10: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) [52046] (3 superfamilies)
   2 curved layers, a/b; parallel beta-sheet; order 1234...N; there are sequence similarities between different superfamilies

4. Superfamily c.10.2: L domain-like [52058] (9 families)
   less regular structure consisting of variable repeats

5. Family c.10.2.7: Ngr ectodomain-like [75142] (7 proteins)
   applies to all domains of a family if the common domain is composed of a different number of small repeating units
   this is a repeat family; one repeat unit is 1xwd C:97-122 found in domain

Proteins:

1. Decorin [117463] (1 species)

   • Species Cow (Bos taurus) [TaxId:9913] [117464] (3 PDB entries)
     Uniprot P21793 52-356

2. Follicle-stimulating hormone receptor [159450] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [159451] (1 PDB entry)
     Uniprot P23945 18-259

3. High affinity nerve growth factor receptor, N-terminal domain [141992] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [141993] (1 PDB entry)
     Uniprot P04629 36-191

4. Reticulon 4 receptor (Nogo-66 receptor, Ngr) [89567] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [89568] (2 PDB entries)

5. Slit [117461] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [117462] (1 PDB entry)
     Uniprot P24014 542-733

6. von Willebrand factor binding domain of glycoprotein Ib alpha [75143] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [75144] (10 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [359229] (1 PDB entry)

7. automated matches [235852] (2 species)
   not a true protein

   1. Species Human (Homo sapiens) [TaxId:9606] [235853] (2 PDB entries)

   2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [255909] (1 PDB entry)

More info for Family c.10.2.7: Ngr ectodomain-like

Timeline for Family c.10.2.7: Ngr ectodomain-like:

• Family c.10.2.7: Ngr ectodomain-like first appeared in SCOP 1.61, called Family c.10.2.7: von Willebrand factor binding domain of glycoprotein Ib alpha
  
• Family c.10.2.7: Ngr ectodomain-like appears in SCOPe 2.07