SCOP 1.67: Domain d1i7ib_: 1i7i B:

Lineage for d1i7ib_ (1i7i B:)

1. Root: SCOP 1.67

2. Class a: All alpha proteins [46456] (202 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (27 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (10 PDB entries)

8. Domain d1i7ib_: 1i7i B: [71126]
   complex with the agonist AZ 242
   complexed with az2

Details for d1i7ib_

PDB Entry: 1i7i, 2.35 Å

PDB Description: crystal structure of the ligand binding domain of human ppar-gamma in complex with the agonist az 242

SCOP Domain Sequences for d1i7ib_:

Sequence, based on SEQRES records:

>d1i7ib_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens)}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiy

Sequence, based on observed residues (ATOM records):

>d1i7ib_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens)}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
ikevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlasl
mnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviil
sgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqll
qvikktetslhpllqeiy

Timeline for d1i7ib_:

• d1i7ib_ first appeared in SCOP 1.61
  
• d1i7ib_ appears in SCOP 1.65
  
• d1i7ib_ appears in SCOP 1.69
  
• d1i7ib_ appears in the current release, SCOPe 2.08