SCOP 1.65: Domain d1gsia_: 1gsi A:

Lineage for d1gsia_ (1gsi A:)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (21 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (16 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidylate kinase [52563] (4 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [69482] (9 PDB entries)

8. Domain d1gsia_: 1gsi A: [70396]
   complexed with act, mg, so4, tmp

Details for d1gsia_

PDB Entry: 1gsi, 1.6 Å

PDB Description: crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with thymidine monophosphate (tmp)

SCOP Domain Sequences for d1gsia_:

Sequence; same for both SEQRES and ATOM records:

>d1gsia_ c.37.1.1 (A:) Thymidylate kinase {Mycobacterium tuberculosis}
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagersrgraqrdpgrardnyerdaelqqrtgavya
elaaqgwggrwlvvgadvdpgrlaatla

Timeline for d1gsia_:

• d1gsia_ first appeared in SCOP 1.61
  
• d1gsia_ appears in SCOP 1.63
  
• d1gsia_ appears in SCOP 1.67
  
• d1gsia_ appears in the current release, SCOPe 2.08