Lineage for d1jpsl1 (1jps L:1-107)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2018294Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2018295Species Engineered (including hybrid species) [88533] (61 PDB entries)
    SQ NA # humanized antidoby; bactericidal Fab-h6831 ! SQ NA # Humanized antibody ! SQ NA # humanized antibody ! SQ NA # engineered antibody
  8. 2018300Domain d1jpsl1: 1jps L:1-107 [67047]
    Other proteins in same PDB: d1jpsh1, d1jpsh2, d1jpsl2, d1jpst1, d1jpst2
    part of humanized Fab D3H44 against human tissue factor

Details for d1jpsl1

PDB Entry: 1jps (more details), 1.85 Å

PDB Description: Crystal structure of tissue factor in complex with humanized Fab D3h44
PDB Compounds: (L:) immunoglobulin Fab D3h44, light chain

SCOPe Domain Sequences for d1jpsl1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1jpsl1 b.1.1.1 (L:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Engineered (including hybrid species)}

SCOPe Domain Coordinates for d1jpsl1:

Click to download the PDB-style file with coordinates for d1jpsl1.
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Timeline for d1jpsl1: