SCOP 1.67: Domain d1jlgb_: 1jlg B:

Lineage for d1jlgb_ (1jlg B:)

1. Root: SCOP 1.67

2. Class e: Multi-domain proteins (alpha and beta) [56572] (40 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (2 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (2 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (71 PDB entries)

8. Domain d1jlgb_: 1jlg B: [66850]
   Other proteins in same PDB: d1jlga1
   complexed with uc1; mutant

Details for d1jlgb_

PDB Entry: 1jlg, 2.6 Å

PDB Description: crystal structure of y188c mutant hiv-1 reverse transcriptase in complex with uc-781

SCOP Domain Sequences for d1jlgb_:

Sequence, based on SEQRES records:

>d1jlgb_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfr
kytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymd
dlcvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpiv
lpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelae
nreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndv
kqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvkl
wyqlekep

Sequence, based on observed residues (ATOM records):

>d1jlgb_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfwgiphpaglkkkksvtvldvgdayfsvpldedfrkyta
ftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlcv
gsdleigqhrtkieelrqhllrwgelhpdkwtvqpivlpekdswtvndiqklvgklnwas
qiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliae
iqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpk
fklpiqketwetwwteywqatwipewefvntpplvklwyqlekep

Timeline for d1jlgb_:

• d1jlgb_ first appeared in SCOP 1.59, called d1jlgb1
  
• d1jlgb_ appears in SCOP 1.65
  
• d1jlgb_ appears in SCOP 1.69
  
• d1jlgb_ appears in the current release, SCOPe 2.08