SCOPe 2.06: Domain d1igxa1: 1igx A:74-584

Lineage for d1igxa1 (1igx A:74-584)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.93: Heme-dependent peroxidases [48112] (1 superfamily)
   multihelical; consists of two all-alpha domains

4. Superfamily a.93.1: Heme-dependent peroxidases [48113] (4 families)

5. Family a.93.1.2: Myeloperoxidase-like [48132] (3 proteins)

6. Protein Prostaglandin H2 synthase [48136] (2 species)
   contains EGF-like module

7. Species Sheep (Ovis aries) [TaxId:9940] [48137] (23 PDB entries)
   Uniprot P05979 32-584

8. Domain d1igxa1: 1igx A:74-584 [66136]
   Other proteins in same PDB: d1igxa2
   complexed with bgc, bog, coh, epa

Details for d1igxa1

PDB Entry: 1igx, 3.1 Å

PDB Description: crystal structure of eicosapentanoic acid bound in the cyclooxygenase channel of prostaglandin endoperoxide h synthase-1.

PDB Compounds: (A:) prostaglandin endoperoxide h synthase-1

SCOPe Domain Sequences for d1igxa1:

Sequence; same for both SEQRES and ATOM records:

>d1igxa1 a.93.1.2 (A:74-584) Prostaglandin H2 synthase {Sheep (Ovis aries) [TaxId: 9940]}
iwtwlrttlrpspsfihfllthgrwlwdfvnatfirdtlmrlvltvrsnlipspptynia
hdyiswesfsnvsyytrilpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqg
tnlmfaffaqhfthqffktsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklk
yqmlngevyppsveeapvlmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvc
dllkaehptwgdeqlfqtarliligetikivieeyvqqlsgyflqlkfdpellfgaqfqy
rnriamefnqlyhwhplmpdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagr
igggrnidhhilhvavdvikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaelee
lygdidalefypglllekchpnsifgesmiemgapfslkgllgnpicspeywkastfgge
vgfnlvktatlkklvclntktcpyvsfhvpd

Timeline for d1igxa1:

• d1igxa1 first appeared in SCOP 1.59
  
• d1igxa1 appears in SCOPe 2.05
  
• d1igxa1 appears in SCOPe 2.07
  
• d1igxa1 appears in the current release, SCOPe 2.08